TWiV 172: Two can be as bad as one

tetramer stainingHosts: Vincent Racaniello and Kathy Spindler

Vincent and Kathy discuss how a virus may cause disease distant from its replication site, then review a day in the life of a senior microbiology professor.

Click the arrow above to play, or right-click to download TWiV 172 (74 MB .mp3, 102 minutes).

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Links for this episode:

Weekly Science Picks

Kathy – Science prize for inquiry-based instruction (Alberts editorial, second winner)
Vincent – The long and winding road to a Ph.D.

Listener Pick of the Week

Greg – Correlation

Send your virology questions and comments to [email protected].

TWiV 171: One is the loneliest number

single virion genomicsHosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Matt Frieman

Matt joins the TWiVarians to review virus production in single cells and single virion genomics.

Click the arrow above to play, or right-click to download TWiV 171 (67 MB .mp3, 92 minutes).

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Links for this episode:

Weekly Science Picks

Matt – H5N1 research discussion
Dickson – The Golden Wand of Medicine by Walter J. Friedlander
Alan – Imagine Science Films
Vincent – E. coli: Good, Bad, and Deadly

Listener Pick of the Week

Daniel – The scale of the Universe
Stefan – A Legacy of Achievement

Send your virology questions and comments to [email protected].

TWiV 170: From variolous effluvia to VLPs

cow-pockHosts: Alan Dove, Rich Condit, and Dickson Despommier

Alan, Rich, and Dickson discuss Edward Jenner’s paper on cowpox vaccine, then move 200 years later to modern vaccines against norovirus, influenza H5N1, and more.

Click the arrow above to play, or right-click to download TWiV 170 (72 MB .mp3, 100 minutes).

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Links for this episode:

Weekly Science Picks

Dickson – High-speed photography of falling drop
Rich – Biotechnology Research in an Age of Terrorism (NAP)
Alan – Lab Report videos (YouTube)

Listener Pick of the Week

Jim – The Blind Spot

Send your virology questions and comments to [email protected].

TWiV 169: Epidemiology causes conclusions (p less than 0.01)

Snow cholera mapHosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Michael Walsh

Michael and the TWiV team review epidemiology basics, including fatality ratios.

Click the arrow above to play, or right-click to download TWiV 169 (64 MB .mp3, 152 minutes).

Right-click this link to download only our discussion on how to read a science paper (22 MB .mp3, 30 minutes).

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Links for this episode:

Weekly Science Picks

Michael – Love my epi
Dickson – Bacteria array detects arsenic
Rich – Dunning-Kruger effect
Alan – Environmental Economics
Vincent – Don’t censor influenza research

Listener Pick of the Week

Simon – The Great Mortality by John Kelly

Send your virology questions and comments to [email protected].

TWiV 168: Super CalTech prophylaxis and ferret runny noses

adeno-associated virusHosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Welkin Johnson

Welkin joins the TWiV team for a discussion of HIV prophylaxis using vectored antibodies, and the influenza H5N1 virus studies in ferrets that were not redacted.

Click the arrow above to play, or right-click to download TWiV 168 (59 MB .mp3, 98 minutes).

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Links for this episode:

Weekly Science Picks

Welkin – Virtual PI (Nature)
Dickson – Drain the Ocean
Rich – Nova: To the Moon
Alan – Robert Falcon Scott on Twitter and the Terra Nova expedition
Vincent – Hello, Mr. Chips (I, Cringely)

Listener Pick of the Week

Charlotte – And the Band Played On

Send your virology questions and comments to [email protected].

TWiV 167: It starts with a cough

Lipkin in ContagionHosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Alan Dove

The complete TWiVome deconstructs the movie Contagion.

Click the arrow above to play, or right-click to download TWiV 167 (53 MB .mp3, 88  minutes).

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Links for this episode:

Weekly Science Picks

Dickson – Guinea Pig Doctors by Jon Franklin
Rich – Learn to appreciate technology and Everythings amazing and nobodys happy (YouTube)
Alan – JD Hooker slide collection
Vincent – iTunes U app and iBooks Author

Listener Pick of the Week

Judi – Makers of Many Things by Eva March Tappan

Send your virology questions and comments to [email protected].

TWiV 166: Breaking and entering

npc1 ebolaHosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Alan Dove

Vincent, Dickson, Rich, and Alan review cell proteins essential for entry of hepatitis C, Ebola, and measles viruses.

Click the arrow above to play, or right-click to download TWiV 166 (59 MB .mp3,  98 minutes).

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Links for this episode:

Weekly Science Picks

Dickson – What are you swimming with?
Rich – Twelve monkeys
Alan – Kindle Touch
Vincent – Microbe news (thanks to Dave Winer)

Listener Pick of the Week

Eric – The Nature of Things with David Suzuki
Lance – Trials and Errors (Wired)

Send your virology questions and comments to [email protected].

TWiV 165: The email zone

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Alan Dove

Vincent, Dickson, Rich, and Alan answer listener questions about XMRV, cytomegalovirus, latency, shingles vaccine, myxomavirus and rabbits, and more.

Click the arrow above to play, or right-click to download TWiV 165 (61 MB .mp3, 102 minutes).

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Links for this episode:

Weekly Science Picks

Dickson – Creation
Rich – America’s Science Decline
Alan – Out of context science
Vincent – The Scientist Top 10 Innovations 2011

Listener Pick of the Week

Jim – Christoph Adami: Finding life we can’t imagine (TED)
Tim – Patient Zero (Radiolab)
Mary – Natural Obsessions by Natalie Angier
Jimmy – Science Exchange

Send your virology questions and comments to [email protected].

TWiV 164: Six steps forward, four steps back

xmrvHosts: Vincent Racaniello, Rich Condit, and Alan Dove

Vincent, Alan, and Rich review ten compelling virology stories of 2011.

Click the arrow above to play, or right-click to download TWiV 164 (60 MB .mp3, 99 minutes).

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Ten virology stories of 2011:

  1. XMRV, CFS, and prostate cancer (TWiV 119, 123, 136, 150)
  2. Influenza H5N1, ferrets, and the NSABB (TWiV 159)
  3. The Panic Virus (TWiV 117)
  4. Polio eradication (TWiV 127, 149)
  5. Viral oncotherapy (TWiV 124, 131, 142, 156)
  6. Hepatitis C virus (TWiV 130, 137, 141)
  7. Zinc finger nuclease and HIV therapy (TWiV 144)
  8. Bacteria help viruses (TWiV 154)
  9. Human papillomaviruses (TWiV 126)
  10. Combating dengue with Wolbachia (TWiV 115, 147)

Links for this episode:

Weekly Science Picks

Rich – Fundamentals of Molecular Virology by Nicholas H. Acheson
Alan – Fetch, with Ruff Ruffman
Vincent – Year end reviews at Rule of 6ix and Contagions

Listener Pick of the Week

Garren – Trillion-frame-per-second video
Judi – iBioMagazine
Ricardo – Brain Picking’s 11 best science books of 2011

Send your virology questions and comments to [email protected].

TWiV 163: What Rous wrought

fungal christmas treeHosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Alan Dove

Vincent, Dickson, Rich, and Alan review the 100 year old finding by Peyton Rous of a transmissible sarcoma of chickens, a discovery that ushered in the era of tumor virology.

Click the arrow above to play, or right-click to download TWiV 163 (61 MB .mp3, 102 minutes).

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Links for this episode:

Weekly Science Picks

Rich – The Log from the Sea of Cortez by John Steinbeck
Alan – Comet rise
Vincent – TWiV iPhone case

Listener Pick of the Week

Ronnie – How fungi celebrate Christmas
Kevin – EcoCyc app
Gabriel – ImmGen app

Send your virology questions and comments to [email protected].

The Hosts of TWiV

Vincent Racaniello, Ph.D.


Brianne Barker, Ph.D.


Rich Condit, Ph.D.


Alan Dove, Ph.D.


Daniel Griffin, M.D.,
Ph.D., CTropMed CTH


Angela Mingarelli, DVM


Jolene Ramsey, Ph.D.


Kathy Spindler, Ph.D.


CLICK FOR MORE INFO

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