The TWiPians solve the case of the Woman With Anemia, Eosinophila, and a Worm in Her Intestine, and discuss a study on the function and druggability of two malarial aspartate proteases.
TWiP 125: Third time’s a charm
- January 21, 2017
- Tagged as: Anopheles, malaria, mosquito, parasite, parasitism, parasitology, Plasmodium falciparum, sporozoite, vaccine
The TWiPonderers solve the case of the Timber Worker with Severe Shaking Chills, and describe an experimental malaria vaccine comprising attenuated sporozoites produced by genetic engineering.
The TWiPanorama solve the case of the Dutch Woman with Wormy Objects in Her Stool, dissect a study on cytoadhesion of malaria infected red blood cells, and introduce Parasitology Superheroes.
The TWiP troika solve the case of the Female from the Bronx, and reveal how feeding on different plants affects mosquito capacity to transmit malaria.
The TWiP-scholars solve the case of the Housewife from Kolkata, discuss mutations in the IL17 gene associated with cerebral malaria, and hear a case presentation from guest Michael Libman.
Vincent, Dickson, and Daniel review how Viagra might be used to block transmission of Plasmodium falciparum, and introduce a new case study.
TWiP 90: A carbuncle is a large furuncle
- May 30, 2015
- Tagged as: CD44, CD55, erythrocyte, forward genetic screen, invasion, malaria, parasite, parasitism, Plasmodium falciparum, siRNA
Vincent, Dickson, and Daniel discuss identification of an erythrocyte protein essential for invasion of Plasmodium falciparum, and introduce a new case study.
TWiP 74: Nature has all the answers, what is your question?
- July 4, 2014
- Tagged as: antigen, egress, malaria, parasite, parasitism, Plasmodium falciparum, red blood cell, schizont, vaccine
Vincent and Dickson review a novel malaria vaccine candidate comprising a parasite protein involved in egress from red blood cells.
Vincent and Dickson discuss an increase in the altitude of malaria distribution in warmer years in the highlands of Colombia and Ethiopia.
Vincent and Dickson meet with Judith Straimer and Marcus Lee to discuss their method for site-specific genome editing in Plasmodium falciparum using zinc finger nucleases.
