The TWiP team solves the case of the Woman Who Vomited Up a Worm, and discuss how malaria transmission intensity can modify the effectiveness of the RTS, S/AS01 vaccine in Africa.
TWiP solves the case of the Adventurous Eater with Areas of Swelling, and discusses an experimental Trypanosoma vivax vaccine comprising an invariant flagellum antigen.
The TWiP Trinity solve the case of the Peace Corps volunteer with diarrhea, and reveal how immunizing against a virus ameliorates exacerbated leishmaniasis.
The TWiPonderers solve the case of the Timber Worker with Severe Shaking Chills, and describe an experimental malaria vaccine comprising attenuated sporozoites produced by genetic engineering.
The TWiP ternion solve the case of the Man from Mexico, and discuss a transgenic toxoplasma vaccine for chickens using Eimeria tenella.
Vincent and Dickson review a novel malaria vaccine candidate comprising a parasite protein involved in egress from red blood cells.
Vincent and Dickson discuss the high diversity of malaria parasites in West African bats, and a vaccine against hookworm.
Vincent and Dickson update the multistate outbreak of cyclosporiasis, discuss the avian malaria parasite P. lophurae, and review protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine.
Vincent, Dickson, and Yosef discuss tetraspanins on the surface of schistosomes as vaccine candidates and immune evasion proteins.
Vincent and Dickson discuss the promising results of a phase III trial of a malaria vaccine in African children.
