TWiP discusses hookworm infection and the phase 1 clinical trial for a hookworm vaccine that could one day protect children from the hookworm anaemia, and reduce transmission of this infection.
The Podfessors solve the case of the Itchy Child from Panama, and discuss competition for blood in human malaria-helminth co-infections.
TWiP 148: Weep and sweep
- March 7, 2018
- Tagged as: B1 cell, B2 cell, goblet cell, hookworm, IgE, mast cell, mucus, parasite, parasitism, parasitology, Stronglyoides
The TWiP-tologists solve the case of the Child in South America With Belly Pain, and reveal how B1 cell IgE blocks parasite clearance by inhibiting mast cell activation by B2 cell IgE.
The TWiPniks docs solve the case of the Female from Peru with Epistaxis, and discuss the effect of community deworming on immunosuppression.
TWiP 62: More bats out of hell
- October 31, 2013
- Tagged as: bat, Gabon, hookworm, malaria, parasite, parasitism, vaccine
Vincent and Dickson discuss the high diversity of malaria parasites in West African bats, and a vaccine against hookworm.
Vincent and Dickson discuss possibly the most socially and politically important nematode of humans, the hookworm Ancylostoma duodenale and Necator americanus.