Tag: malaria

• Episodes

TWiP 196: Naked eye entomologist

• July 12, 2021
• Tagged as: body louse, circumsporozoite protein, malaria, mRNA vaccine, parasite, parasitism, parasitology, Pediculus humanus

TWiP solves the case of the Homeless Man With Skin Issues, and discusses an experimental mRNA based malaria vaccine.

• Episodes

TWiP 190: But Doc, what could it be?

• December 8, 2020
• Tagged as: abdominal mass, COVID-19, Echinococcus, hydatid cyst, malaria, NGO, pandemic, parasite, parasitism, parasitology

Christina from Glasgow returns to help the TWiPlets solve the case of the Ghanian Woman with Abdominal Mass, followed by discussion of the impact of COVID-19 on malaria morbidity and mortality in Africa.

• Episodes

TWiP 187: Granny’s granuloma

• August 29, 2020
• Tagged as: Chagas disease, granuloma, heme oxygenase, leishmaniasis, malaria, parasite, parasitism, parasitology, Toxocara

Dickson, Daniel and Vincent solve the case of the Middle Aged Woman with Loss of Vision in One Eye, and discuss the role of heme oxygenase in the various protozoan infections.

• Episodes

TWiP 186: Not rationing rationality

• August 1, 2020
• Tagged as: Babesia microti, babesiosis, cytokinesis, electron microscopy, malaria, mosquito, parasite, parasitism, parasitology, Plasmodium falciparum, tick, West Nile Virus

Dickson, Daniel and Vincent solve the case of the Elder Gardener Feeling Poorly, and discuss the three-dimensional ultrastructure of Plasmodium falciparum during cytokinesis.

• Episodes

TWiP 185: Latrinalia

• July 2, 2020
• Tagged as: intrinsic clock, intrinsic oscillator, malaria, parasite, parasitism, parasitology, tertian fever

Dickson, Daniel and Vincent solve the case of the Wife of a Guy with Cyclospora Diarrhea, and discuss the discovery of an intrinsic oscillator that drives the bloodstream stage cycle of the malaria parasite.

• Episodes

TWiP 184: The hunter gets captured by the game

• June 6, 2020
• Tagged as: Anopheles, COVID-19, cyclospora, endosymbiont, malaria, microsporidian, mosquito, parasite, parasitism, parasitology, Plasmodium, watery diarrhea, wolbachia

Dickson, Daniel and Vincent solve the case of the Safari Goer With Watery Diarrhea, and explain how a microsporidian endosymbiont of Anopheles mosquitoes might impair the transmission of malaria.

• Episodes

TWiP 180: A spleen palaver

• February 8, 2020
• Tagged as: artemisinin, clathrin, endocytosis, hemoglobin, kelch13, malaria, parasite, parasite food vacuole, parasitism, parasitology, Plasmodium, spleen, splenomegaly, Uganda

The TWiP professors solve the case of the Ugandan Child with Splenomegaly, and reveal that mutations in the P. falciparum genome that confer artemisinin resistance interfere with endocytic uptake of hemoglobin.

• Episodes

TWiP 179: Verminous visitors

• January 11, 2020
• Tagged as: Ascaris, hemoglobin, macaque, malaria, malarial anemia, nonhuman primate, parasite, parasitism, parasitology, pathogenesis, roundworm

The TWiP DVD solve the case of the Child Who Passed Worms, and discuss a non-human primate model for severe malarial anemia.

• Episodes

TWiP 178: The shadowlands of medicine

• December 4, 2019
• Tagged as: antimalaria drug, Chilomastix mesnili, Dientamoeba fragilis, gastroenteritis, malaria, ova and parasites, parasite parasitism, parasitology, Plasmodium falciparum, protein kinase

The Knights of the TWiP solve the case of the Man Who Lost Weight, and discuss a Plasmodium protein kinase that is a malarial drug target.

• Episodes

TWiP 175: None alone pathognomonic

• September 4, 2019
• Tagged as: erythrocyte invasion, Kala Azar, Leishmania donovani, leishmaniasis, malaria, malaria vaccine, neutralizing antibodies, non-neutralizing antibodies, parasite, parasitism, parasitology, PfRH5, sandfly, Sudan

The TWiP’ers solve the case of the Sudanese Boy With Fever, and reveal antibodies that slow invasion of red blood cells potentiate other malaria-blocking antibodies