TWiM 248: Borgs are real

Mark Martin returns to TWiM to discuss ways to increase diversity in our field, and the discovery of Borgs, giant extrachromosomal elements with the potential to augment methane oxidation.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt

Guest: Mark O. Martin

Right click to download TWiM #248 (40 MB .mp3, 54 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 247: Therapy with paleofeces and phages

TWiM explores whether ‘rewilding’ is a way to get back our missing gut microbes, and failure of bacteriophage therapy due to the production of neutralizing antibodies.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt

Right click to download TWiM #247 (40 MB .mp3, 54 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 246: Intracellular niche and passage

The TWiM folk explore disruption of a Burkholderia intracellular niche by a cell death program, and an increase in Brucella infectiousness after intracellular passage.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt

Right click to download TWiM #246 (40 MB .mp3, 54 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 245: Bacteria that protect bees from fungi

In this episode, how polysaccharides keep cyanobacteria afloat in the oceans so that they can carry out photosynthesis, and a symbiotic bacterium that protects honey bees from fungal infections.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt

Right click to download TWiM #245 (40 MB .mp3, 54 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 244: Chewing for chicha

Foodie TWiM reveals that bacteria in human saliva are major components of Ecuadorian indigenous beers, and an unusual E. coli that produces atypical light cream-colored colonies in chromogenic agar.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt

Right click to download TWiM #244 (40 MB .mp3, 54 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 243: Beef and bacillus

TWiM continues its food arc with an examination of the effect of peroxyacetic acid spray on the microbiome and sensory properties of beef, and explores asymmetry of the cell division machinery during sporulation.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt

Right click to download TWiM #243 (40 MB .mp3, 54 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 242: Sourdough starter microbiome

TWiM reveals the microbiome of sourdough starter cultures, and discovery of a novel family of prokaryotic nanocompartments involved in the metabolism of sulfur.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt

Right click to download TWiM #242 (40 MB .mp3, 54 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 241: What does flu do to your poo?

TWiM explains how Vibrio biofilms are dispersed by polyamine signals, and the induction of inappetence by respiratory virus infection which causes alteration of the gut microbiome.

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt

Right click to download TWiM #241 (32 MB .mp3, 44 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 240: Aspirin, colorectal cancer, and Fusobacterium

TWiM reviews aspirin modulation of Fusobacterium nucleatum, a microbe that has been associated with colorectal cancer, and Elio tells us ‘What are vaccines’, a talk he recently gave to members of his community.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt

Right click to download TWiM #240 (32 MB .mp3, 44 minutes)

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Fecal microbiota transplant for dysbiosis (NEJM)

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 239: The phoenix of bacteria

The TWiM team reviews how variants of P. aeruginosa survive antimicrobial treatment, and a decrease in the antimicrobial resistance of the gut microbiome in the presence of the fungus C. albicans.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt

Right click to download TWiM #239 (32 MB .mp3, 44 minutes)

Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

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Links for this episode:

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

About the Hosts of TWiM

Vincent Racaniello, Ph.D. (@profvrr) is Higgins Professor of Microbiology & Immunology at Columbia University Medical Center. He has been studying viruses for over 40 years. He teaches virology to undergraduate and graduate students, as well as medical, dental, and nursing students. His lectures are available online at iTunes University, YouTube, and Coursera.


Michael Schmidt, Ph.D. (TWiM) is the Professor and Vice Chairman of Microbiology and Immunology and Director of the Office of Special Programs at the Medical College of South Carolina. Dr. Schmidt is leading a team of infectious disease specialists from three health sciences centers and engineers from industry.

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