TWiM 14: Vomocytosis and microbial transistors

geobacterHosts: Stanley Maloy, Margaret McFall-Ngai, Michael Schmidt, and Elio Schaechter

On episode #14 of the podcast This Week in Microbiology, Stanley, Margaret, Michael and Elio review how the fungus Cryptococcus escapes from macrophages, and electrical conductivity in nanowires formed by the bacterium Geobacter.

Download TWiM #14 (49 MB, .mp3, 68 minutes).

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TWiM 13: Probiotics and inflammasomes: Telling good bacteria from the bad

colonic epitheliumHosts: Stanley Maloy, Jo Handelsman, Michael Schmidt, and Elio Schaechter

On episode #13 of the podcast This Week in Microbiology, Stanley, Jo, Michael and Elio discuss how colonic microbial ecology and risk for colitis are regulated by an inflammasome, and amelioration of intestinal inflammation in mice by delivery of a probiotic-derived soluble protein to the colon.

Download TWiM #13 (42 MB, .mp3, 58 minutes).

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TWiM 12: Photothermal nanoblades and genome engineering

chicken_farm1Hosts: Vincent Racaniello, Michael Schmidt, Margaret McFall-Ngai, and Elio Schaechter

On episode #12 of the podcast This Week in Microbiology, Vincent, Margaret, Michael and Elio review the use of photothermal nanoblades to dissect the Burkholderia intracellular life cycle, and manipulation of chromosomes in vivo for genome-wide codon replacement in E. coli.

Download TWiM #12 (52 MB, .mp3, 75 minutes).

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TWiM 11: Chickens, antibiotics, and asthma

chicken_farm1

Hosts: Vincent Racaniello, Michael Schmidt, Margaret McFall-Ngai, and Elio Schaechter.

On episode #11 of the podcast This Week in Microbiology, Vincent, Margaret, Michael and Elio review the presence of extended spectrum beta-lactamase genes in chicken meat and in humans, and a beneficial effect of Helicobacter pylori colonization on the development of allergen-induced asthma.

Download TWiM #11 (50 MB, .mp3, 73 minutes).

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TWiM 10: A symbiotic cloaking device

Euprymna scolopes also known as the Hawaiian Bobtail SquidHosts: Vincent Racaniello, Michael Schmidt, Dickson Despommier, Margaret McFall-Ngai, and Elio Schaechter

On episode #10 of the podcast This Week in Microbiology, Vincent, Margaret, Elio, Michael and Dickson discuss the symbiosis between the Hawaiian bobtail squid and the luminous, gram-negative bacterium Vibrio fischeri.

Download TWiM #10 (47 MB, .mp3, 68 minutes).

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TWiM 9: Bean sprouts and E. coli O104:H4

beansproutsHosts: Vincent Racaniello, Cliff Mintz, and Michael Schmidt

On episode #9 of the podcast This Week in Microbiology, Vincent, Cliff, Elio, and Michael review the outbreak of bloody diarrhea and hemolytic uremic syndrome in Germany caused by Shiga toxin-producing Escherichia coli O104:H4.

Download TWiM #9 (53 MB, .mp3, 76 minutes).

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TWiM 8: Live in NOLA

Hosts: Vincent Racaniello, Michael Schmidt, Stan Maloy, Andreas Baümler, Nicole Dubilier, and Paul Rainey.

Vincent, Michael, and Stanley recorded episode #8 of the podcast This Week in Microbiology live at the 2011 ASM General Meeting in New Orleans, with guests Andreas Baümler, Nicole Dubilier, and Paul Rainey. They spoke about how pathogens benefit from disease, symbioses between chemosynthetic bacteria and marine invertebrates, and repetitive sequences in bacteria.



Download TWiM #8 (60 MB, .mp3, 86.5 minutes).

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TWiM 7: Cycles of life and death, light and dark

Cyanobacteria in Lake LittoistenjrviHosts: Vincent Racaniello, Margaret McFall-Ngai, Cliff Mintz, Elio Schaechter, and Michael Schmidt

On episode #7 of the podcast This Week in Microbiology, Vincent, Cliff, Elio, Margaret, and Michael discuss programmed cell death in E. coli, and the daily synthesis and degradation of enzymes needed for photosynthesis and nitrogen fixation by cyanobacteria.

Download TWiM #7 (44.5 MB, .mp3, 64 minutes).

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Image of Cyanobacteria in Lake Littoistenjärvi by Stefe via flickr

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TWiM 6: Antibacterial therapy with bacteriophage: Reality or fiction?

bacteriophage_modelHosts: Vincent Racaniello, Cliff Mintz, Michael Schmidt, and Elio Schaechter

On episode #6 of the podcast This Week in Microbiology, Vincent, Cliff, Michael and Elio review the use of bacteriophages to manage infections, and the presence of antibiotic resistance genes in bacteriophages from urban sewage and river water.

Download TWiM #6 (57 MB .mp3, 82 minutes).

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The model of bacteriophage T4 shown in the photo is described here.

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TWiM 5: Mercury-methylating Desulfovibrio and antimicrobial nanoparticles

thumb_biofilm_of_desulfovibrio_desulfuricansHosts: Vincent Racaniello, Cliff Mintz, Michael Schmidt, and Ronald Atlas

On episode #5 of the podcast This Week in Microbiology, Vincent, Cliff, Michael and Ron discuss the genome sequence of a mercury-methylating bacterium and the antimicrobial effects of nanoparticles.

Download TWiM #5 (52.5 MB .mp3, 76 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Image of Biofilm of Desulfovibrio desulfuricans by PNNL – Pacific Northwest National Laboratory via flickr

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About the Hosts of TWiM

Vincent Racaniello, Ph.D. (@profvrr) is Higgins Professor of Microbiology & Immunology at Columbia University Medical Center. He has been studying viruses for over 40 years. He teaches virology to undergraduate and graduate students, as well as medical, dental, and nursing students. His lectures are available online at iTunes University, YouTube, and Coursera.


Michael Schmidt, Ph.D. (TWiM) is the Professor and Vice Chairman of Microbiology and Immunology and Director of the Office of Special Programs at the Medical College of South Carolina. Dr. Schmidt is leading a team of infectious disease specialists from three health sciences centers and engineers from industry.

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