TWiM 34: Doing the DISCO with Emiliania

coccolithophoreHosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

Vincent, Michael, and Elio discuss changing populations of Emiliania huxleyi and their viruses in the North and Black Seas.

Download TWiM #34 (50 MB .mp3, 69 minutes).

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TWiM 33: Tuning the immune organ

segmented filamentous bacteriaHosts: Vincent Racaniello, Michael Schmidt, and Ivalyo Ivanov

Vincent, Michael, and Ivo review the requirement for segmented, filamentous bacteria for the induction of a specific type of helper T cell in the gut.

Download TWiM #33 (49 MB .mp3, 68 minutes).

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TWiM #32: Not the shadow biosphere

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Rosie Redfield.

Vincent, Elio and Michael speak with Rosie Redfield about her evidence that a bacterium cannot grow on arsenic instead of phosphorus. Mono Lake

Right click to download TWiM #32 (49 MB, .mp3, 67 minutes).

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Send your microbiology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

TWiM 31: Screen door on a submarine

tamHosts: Vincent Racaniello, Jo Handelsman, and Michael Schmidt

Vincent, Jo, and Michael discuss an archetypal protein transport system in bacterial outer membranes, and evidence that gut microbial enterotypes might not fall into defined groups.

 

Download TWiM #31 (55 MB, .mp3, 75 minutes).

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TWiM 30: Unraveling melioidosis and insulin resistance

Burkholderia pseudomalleiHosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

On episode #30 of the podcast, Vincent, Elio, and Michael review how a toxin from Burkholderia pseudomallei inhibits protein synthesis, and the role of the gut microbiome in modulating insulin resistance in mice lacking an innate immune sensor.

Download TWiM #30 (50 MB, .mp3, 70 minutes).

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TWiM 29: Death and an iron-loaded spike

phage spikeHosts: Vincent Racaniello and Stanley Maloy

On episode #29 of the podcast, Vincent and Stanley review how a phage pierces the cell membrane with an iron-loaded spike, and two programmed cell death systems in E. coli.

Download TWiM #29 (46 MB, .mp3, 63 minutes).

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TWiM 28: Not unorganized bags of enzymes

caulobacterHosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

On episode #28 of the podcast, Vincent, Michael, and Elio review how competition within a host drives virulence of Streptococcus pneumoniae, and the expanding universe of the bacterial cytoskeleton.

 

Download TWiM #28 (53.5 MB, .mp3, 77 minutes).

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TWiM 27: An inflamed gut is good for Salmonella

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

On episode #27 of the podcast, Vincent, Elio, and Michael review how inflammation allows Salmonella to compete with fermenting gut microbes, and a riboswitch in bacterial and Archeal species that is triggered by fluoride.

Download TWiM #27 (52 MB, .mp3, 75 minutes).

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Listener pick of the week:

Trudy – The Ghost Map by Steven Johnson

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TWiM 26: Suum cuique

minitrapHosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

On episode #26 of the podcast, Vincent, Elio, and Michael discuss the finding of Sutterella species in the gut of autistic children, and methods for cultivating oral bacteria.

Download TWiM #26 (54 MB, .mp3, 75 minutes).

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TWiM 25: Magnetotactic bacteria and totally drug resistant TB

break_magnetHosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

On episode #25 of the podcast, Vincent, Elio, and Michael review bacteria that use the earth’s magnetic field for navigation, and identification of totally drug resistant Mycobacterium tuberculosis.

Download TWiM #25 (53 MB, .mp3, 77 minutes).

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About the Hosts of TWiM

Vincent Racaniello, Ph.D. (@profvrr) is Higgins Professor of Microbiology & Immunology at Columbia University Medical Center. He has been studying viruses for over 40 years. He teaches virology to undergraduate and graduate students, as well as medical, dental, and nursing students. His lectures are available online at iTunes University, YouTube, and Coursera.


Michael Schmidt, Ph.D. (TWiM) is the Professor and Vice Chairman of Microbiology and Immunology and Director of the Office of Special Programs at the Medical College of South Carolina. Dr. Schmidt is leading a team of infectious disease specialists from three health sciences centers and engineers from industry.

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