TWiM reveals a new population in the blue cheese-making fungus Penicillium roqueforti and identification of a quorum-sensing autoinducer and siderophore in uropathogenic Escherichia coli.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #302 (51 MB .mp3, 70 minutes)

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Music used on TWiM is by Ronald Jenkees.

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TWiM reveals a database of genome sequences of thousands of Mycobaterium tuberculosis, allowing association with resistance phenotypes to 13 antibiotics, and microbe-derived uremic solutes that enhance thrombosis potential in the host.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #302 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM describes the mechanism for the S. aureus itch and scratch induced skin damage, and discovery of a novel class of antibiotics that targets the lipopolysaccharide transporter.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #302 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

A highly reduced TWiM team presents a study of the use of phage diversity in cell-free DNA to identify bacterial pathogens in human sepsis cases, and the evolution, persistence, and host adaptation of a gonococcal antimicrobial resistance plasmid that emerged in the pre-antibiotic era.

Hosts: Vincent Racaniello and Petra Levin

Right click to download TWiM #301 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

On the occasion of TWiM’s 300th episode, we discuss how two college students found a new antibiotic in soil, Barbara Iglewski’s passing, and Elio returns for an appearance.

Hosts: Vincent RacanielloMichael Schmidt, Michele Swanson and Petra Levin

Guest: Elio Schaechter

Right click to download TWiM #300 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

From ASM’s Conference for Undergraduate Educators 2023 in Phoenix, TWiM speaks with  Amaya Garcia Costas and Gwendolyn Knapp about their approaches to undergraduate microbiology education, and how they use TWiM as part of their curricula.

Hosts: Vincent RacanielloMichael Schmidt, Michele Swanson and Petra Levin

Guests: Amaya Garcia Costas and Gwendolyn Knapp

Right click to download TWiM #299 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM provides thoughts on providing better training for a non-academic career, and help celebrate Black in Microbiology Week with a 2023 paper by Ari Kozik, a co-founder of Black Microbiologists Association and Assistant Professor at the University of Michigan.

Hosts: Vincent RacanielloMichael Schmidt, Michele Swanson and Petra Levin

Right click to download TWiM #298 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

Become a Patron of TWiM!

Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM reviews how a coating of lipoproteins provides a stabilizing environment on the inner membrane of Bacillus subtilis spores, and a miniaturized device that integrates genetically engineered probiotic biosensors with a custom-designed photodetector and readout chip to track mediators of inflammation in the gastrointestinal tract

Hosts: Vincent RacanielloMichael Schmidt, and Petra Levin

Right click to download TWiM #297 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

Become a Patron of TWiM!

Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM discusses a dispute about whether the mycobiome plays a role in the development of cancer, and the structure and function of channels that are delivered to plant cells by pathogenic bacteria.

Hosts: Vincent RacanielloMichael Schmidt, and Petra Levin

Right click to download TWiM #296 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

Become a Patron of TWiM!

Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM explains how phages avoid tRNA-targeting host defenses, and discovery of a new antibiotic from an uncultured bacterium that binds to an immutable target.

Hosts: Vincent RacanielloMichael Schmidt, and Petra Levin

Right click to download TWiM #295 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

Become a Patron of TWiM!

Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv