TWiM 298: Impact of lung microbiome and racial disparities on asthma

TWiM provides thoughts on providing better training for a non-academic career, and help celebrate Black in Microbiology Week with a 2023 paper by Ari Kozik, a co-founder of Black Microbiologists Association and Assistant Professor at the University of Michigan.

Hosts: Vincent Racaniello,  Michael Schmidt, Michele Swanson and Petra Levin

Right click to download TWiM #298 (51 MB .mp3, 70 minutes)

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Music used on TWiM is by Ronald Jenkees.

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TWiM 297: Bacterial-electronic sensor pill

TWiM reviews how a coating of lipoproteins provides a stabilizing environment on the inner membrane of Bacillus subtilis spores, and a miniaturized device that integrates genetically engineered probiotic biosensors with a custom-designed photodetector and readout chip to track mediators of inflammation in the gastrointestinal tract

Hosts: Vincent Racaniello,  Michael Schmidt, and Petra Levin

Right click to download TWiM #297 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 296: Bacterial channels in plant cells

TWiM discusses a dispute about whether the mycobiome plays a role in the development of cancer, and the structure and function of channels that are delivered to plant cells by pathogenic bacteria.

Hosts: Vincent Racaniello,  Michael Schmidt, and Petra Levin

Right click to download TWiM #296 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

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TWiM 295: Uncultured and unmutable

TWiM explains how phages avoid tRNA-targeting host defenses, and discovery of a new antibiotic from an uncultured bacterium that binds to an immutable target.

Hosts: Vincent Racaniello,  Michael Schmidt, and Petra Levin

Right click to download TWiM #295 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

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TWiM 294: You’ll scream after ice cream

TWiM reveals that the ice cream manufacturing environment harbors psychrotrophic bacteria, and identification of a deadly bacterial strain causing widespread deaths of newborns in Uganda.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #294 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 293: Aerosol phage therapy, alpha-gal aptamers for MRSA

TWiM explains personalized aerosilized phage therapy for a chronic lung infection, and using the combination of antibiotic and a DNA molecule that binds alpha-gal to reduce S. aureus infection in vivo.

Hosts: Vincent Racaniello and Michael Schmidt

Right click to download TWiM #293 (51 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 292: Breast milk bioactives

TWiM reveals that breast milk bioactives are essential for development of the infant microbiome and immunity, and how capsule mutants of Klebsiella pneumoniae can affect bacterial pathogenesis.

Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin

Right click to download TWiM #292 (43 MB .mp3, 60 minutes)

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 291: Biogeography of tectonics and teeth

TWiM explains how photoferrotrophic bacteria initiated plate tectonics over 2500 million years ago, and how two bacteria work together to cause childhood tooth decay.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

Guest: Mark O. Martin

Right click to download TWiM #291 (45 MB .mp3, 62 minutes)

Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 290: Houston, we have Mimi Goldschmidt

From ASM Microbe 2023 in Houston, TWiM speaks with Mimi Goldschmidt about her remarkable career in microbiology which included training astronauts to safely bring moon rocks back to Earth.

Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin

Guest: Mimi Goldschmidt

Right click to download TWiM #290 (34 MB .mp3, 47 minutes)

Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 289: Viral defense and counter-defense

TWiM highlights viral defense and counter-defense: cGAS mediated ubiquitination to counter infection, and viral sponges that sequester nucleotide signals to inactivate immunity.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Petra Levin

Right click to download TWiM #289 (42 MB .mp3, 58 minutes)

Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.

Become a Patron of TWiM!

Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to twim@microbe.tv

About the Hosts of TWiM

Vincent Racaniello, Ph.D. (@profvrr) is Higgins Professor of Microbiology & Immunology at Columbia University Medical Center. He has been studying viruses for over 40 years. He teaches virology to undergraduate and graduate students, as well as medical, dental, and nursing students. His lectures are available online at iTunes University, YouTube, and Coursera.


Michael Schmidt, Ph.D. (TWiM) is the Professor and Vice Chairman of Microbiology and Immunology and Director of the Office of Special Programs at the Medical College of South Carolina. Dr. Schmidt is leading a team of infectious disease specialists from three health sciences centers and engineers from industry.

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