TWiM 49: Grape-like clusters

Staphylococcus aureusHosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

Vincent, Michael, and Elio discuss the HIV co-receptor CCR5 as a receptor for S. aureus leukotoxin ED, and the vineyard yeast microbiome.

Download TWiM #49 (53 MB .mp3, 73 minutes).

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TWiM 48: It’s all about direction

antibody orientationHosts: Vincent Racaniello, Michael Schmidt, and Jo Handelsman

Vincent, Michael, and Jo discuss how subtle gender bias of science faculty favors male students, and the relationship of invasive infection and antibody orientation at bacterial surfaces.

Download TWiM #48 (52 MB .mp3, 76 minutes).

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TWiM 47: Resistance on the surface

Bacterial conjugation AJ CannHosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

Vincent, Michael, and Elio discuss the horizontal transfer of antibiotic resistance genes on metal surfaces, and using bacteriophage to reverse antibiotic resistance.

Download TWiM #47 (49 MB .mp3, 71 minutes).

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TWiM 46: Spore!

sporulationHosts: Vincent Racaniello,Michael Schmidt, Elio Schaechter and Jonathan Dworkin

Vincent, Michael, and Elio meet up with Jonathan Dworkin to discuss how bacteria form spores and how they return to vegetative growth.

Download TWiM #46 (50 MB .mp3, 70 minutes).

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TWiM 45: Secreted nucleic acids RIG a STING

maskHosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

Vincent, Michael, and Elio review innate immune sensing of Listeria secreted bacterial nucleic acids, and how Wolbachia enhances egg production in Drosophila.

Download TWiM #45 (52 MB .mp3, 71 minutes).

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TWiM 44: Phage interruptus

listeria lifecycleHosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

Vincent, Michael, Elio discuss the role of prophage excision in exit of Listeria from the phagosome, and analysis of bacterial communities in saliva.

Download TWiM #44 (48 MB .mp3, 66 minutes).

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TWiM 43: Bacterial caveolae and zapping acne with phages

caveolaeHosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

Vincent, Michael, Elio review formation of caveolae in a bacterium, and the limited genetic diversity and broad killing activity of P. acnes bacteriophages.

Download TWiM #43 (55 MB .mp3, 79 minutes).

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TWiM 42: Staphylococcus, a three-star pathogen

S aureus blood agarHosts: Vincent Racaniello, Joseph John, Michael Schmidt, and Elio Schaechter

Vincent, Michael, Elio, and Joe review highlights of the 15th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI) in Lyon, France.

Download TWiM #42 (52 MB .mp3, 71 minutes).

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TWiM 41: ICAAC live in San Francisco

Hosts: Vincent Racaniello, Michael Schmidt, William Bishai, John Brownstein, and Victor Nizet.

Vincent and Michael travel to San Francisco for the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), where they meet with Bill, John, and Victor to discuss tuberculosis, monitoring infectious disease outbreaks with online data, and outside-the-box approaches to antibacterial therapy.



Download TWiM #41 (48 MB .mp3, 103 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Send your microbiology questions and comments to twim@microbe.tv

TWiM 40: A mecca for microbiology

Hosts: Vincent Racaniello, Stanley Maloy, Waclaw Szybalski, and John Kirby

Vincent and Stanley meet with Waclaw Szybalski and John Kirby at Cold Spring Harbor Laboratory on the occasion of its designation as a Milestones in Microbiology site. They reminisce about how the well known laboratory has advanced the science and teaching of microbiology, and discuss John’s work on the soil dwelling, predatory myxobacteria.



Download TWiM #40 (45 MB .mp3, 62 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Send your microbiology questions and comments to twim@microbe.tv

 

About the Hosts of TWiM

Vincent Racaniello, Ph.D. (@profvrr) is Higgins Professor of Microbiology & Immunology at Columbia University Medical Center. He has been studying viruses for over 40 years. He teaches virology to undergraduate and graduate students, as well as medical, dental, and nursing students. His lectures are available online at iTunes University, YouTube, and Coursera.


Michael Schmidt, Ph.D. (TWiM) is the Professor and Vice Chairman of Microbiology and Immunology and Director of the Office of Special Programs at the Medical College of South Carolina. Dr. Schmidt is leading a team of infectious disease specialists from three health sciences centers and engineers from industry.

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