TWiM explains how spindle-shaped Archaeal viruses evolved from rod-shaped ancestors to package a larger genome, and transcriptional recording by CRISPR acquisition from RNA.

Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin

Right click to download TWiM #266 (37 MB .mp3, 52 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM explains the discovery of hotspots of genetic variation containing reservoirs of anti-phage systems in E. coli phages and their parasitic satellites, and pathogen desiccation tolerance promoted by hydrophilins.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #265 (41 MB .mp3, 57 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM reveals that the atypical antipsychotic quetiapine promotes multiple antibiotic resistance in E. coli, and treatment with Bifidobacterium lactis probiotic benefits patients with coronary artery disease.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

Right click to download TWiM #264 (48 MB .mp3, 66 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM explains the use of lavender oil to disrupt Listeria biofilms, and how treatment of catheters with liquid silicone reduces associated urinary tract infections.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Petra Levin

Right click to download TWiM #263 (57 MB .mp3, 70 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM welcomes new host Petra, and explains how a small protein helps ensure that E. coli utilizes a preferred carbon source, and a screening strategy to identify inhibitors of the type IV secretion system that is essential for virulence of a variety of bacterial pathogens.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

Right click to download TWiM #262 (57 MB .mp3, 70 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Mark returns to TWiM to join in a discussion of soil microbiota as game-changers in restoration of degraded lands, and discovery of a centimeter-long bacterium, the biggest yet discovered.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

Guest: Mark O. Martin

Right click to download TWiM #261 (57 MB .mp3, 70 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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In this food-centric TWiM, we reveal the microbiomes of carnivorous vulture bees and of Gala apples from all over the world.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

Right click to download TWiM #260 (45 MB .mp3, 62 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Mark Martin returns to TWiM for a discussion of the frightening global burden of bacterial antibiotic resistance, and a solution to the problem of daylight nitrogen fixation in a cyanobacterium, despite the incompatibility of nitrogenase with oxygen produced during photosynthesis.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt

Guest: Mark O. Martin

Right click to download TWiM #259 (45 MB .mp3, 62 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM explains how bacterial symbionts regulate tick blood feeding activity, and the reasons why antibiotics exist.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

Right click to download TWiM #258 (45 MB .mp3, 61 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

On this episode of TWiM, how phages prevent other phages from invading their hosts without blocking their own reproduction, and plastic-degrading potential of microbes across the Earth.

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt

Right click to download TWiM #257 (45 MB .mp3, 61 minutes)

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Links for this episode:

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv