This Week in Microbiology

TWiM 22: Microbiology 911

December 14, 2011

Hosts: Vincent Racaniello, Michael Schmidt, and Al Sacchetti

On episode #22 of the podcast This Week in Microbiology, Vincent and Michael speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about microbial infections encountered in the emergency room.

Download TWiM #22 (48 MB, .mp3, 98 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Al Sacchetti wins 2010 ACEP Award
A pathogen’s Swiss army knife (Small Things Considered)
S. aureus: Superbug, supergenome? (Trends in Micro)
Letters read on TWiM #22

Send your microbiology questions and comments to [email protected]

TWiM 21: Symbiotic margheritas

November 30, 2011

Hosts: Vincent Racaniello and Elio Schaechter

On episode #21 of the podcast This Week in Microbiology, Vincent and Elio discuss an ancient symbiosis between Alphaproteobacteria and catenulid flatworms, and a toxin from Helicobacter pylori that engages the mitochondrial fission machinery to induce host cell death.

Download TWiM #21 (50 MB, .mp3, 68 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Paracatenula, an ancient symbiosis (PNAS)
Review on symbiotic diversity in marine animals (Nat Rev Micro)
Helicobacter pylori vacuolating cytotoxin A (PNAS)
Review of H. pylori VacA (Nat Rev Micro)
Viral desserts (Virus Talk)
Letters read on TWiM #21

Send your microbiology questions and comments to [email protected]

TWiM 20: Facebook for bacteria

November 16, 2011

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

On episode #20 of the podcast This Week in Microbiology, Vincent, Michael, and Elio follow up on the outbreaks of E. coli in Germany and cholera in Haiti, then discuss genes that confer self-identity to Proteus mirabilis.

Download TWiM #20 (49 MB, .mp3, 68 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

German outbreak of E. coli O104:H4 associated with sprouts (NEJM)
South Asia not Nepal may be source of Haitian cholera strain (mBio)
Identity gene expression in Proteus mirabilis (J. Bacteriol.)
Proteus swarm movie (YouTube)
Proteus moves at a speed of 4 x 10-5 mph
Education resources at ASM
Letters read on TWiM #20

Send your microbiology questions and comments [email protected]

TWiM 19: Your microbiome is what you eat

November 2, 2011

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Jo Handelsman

On episode #19 of the podcast This Week in Microbiology, Vincent, Michael, Elio, and Jo discuss the genome sequence of Y. pestis from victims of the Black Death, and the effect of diet on gut microbial enterotypes.

Download TWiM #19 (43 MB, .mp3, 60 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Yersinia pestis genome sequence from Black Death victims (Nature)
Black Death genome fished out of East Smithfield (Contagions)
Brief primer on Yersinia
Dietary patterns and gut microbial enterotypes (Science)
The guts of dietary habit (Science)
Review of human gut microbiome (Ann Rev Micro)
Letters read on TWiM #19

Send your microbiology questions and comments to [email protected]

TWiM 18: Escherichia coli K-12, an emerging pathogen?

October 19, 2011

Hosts: Vincent Racaniello, Michael Schmidt, Stanley Maloy and Elio Schaechter

On episode #18 of the podcast This Week in Microbiology, Vincent, Michael, Elio, and Stanley explain how to make the human intestinal commensal and benign laboratory bacterium Escherichia coli K-12 into an invasive organism, and the unearthing of century-old spores in New York City.

Download TWiM #18 (54 MB, .mp3, 74 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Send your microbiology questions and comments to [email protected]

TWiM 17: Debugging endosymbiosis

October 5, 2011

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

On episode #17 of the podcast This Week in Microbiology, Vincent, Michael and Elio focus on endosymbiosis: the rapid spread of Rickettsia in whitefiles, and a metabolic patchwork in nested symbionts of mealybugs.

Download TWiM #17 (51 MB, .mp3, 70 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Nested symbiosis in mealybugs (Curr Bio)
A bug in a bug in a bug (STC)
Rapid spread of an endosymbiont in whitefly (Science)
Instant evolution in whiteflies (UANews)
Letters read on TWiM #17

Send your microbiology questions and comments to [email protected]

TWiM 16: ICAAC Live

September 22, 2011

Hosts: Vincent Racaniello, Michael Schmidt, Arturo Casadevall, Stuart Levy, and David Livermore

On episode #16 of the podcast This Week in Microbiology, Vincent, Michael, Arturo, Stuart, and David converse about antimicrobial resistance and why most fungi do not cause disease at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

Download TWiM #16 (65 MB, .mp3, 90 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Need for new antibacterials (J Antimicr Chem)
Consumer antibacterial soaps (Clin Inf Dis)
Endothermy and fungal growth (mBio)
Bat white-nose syndrome (Microbe)
Chytrid fungus in amphibians

Send your microbiology questions and comments to [email protected]

TWiM 15: Microbial long distance relationships

September 7, 2011

Hosts: Vincent Racaniello, Michael Schmidt and Jo Handelsman

On episode #15 of the podcast This Week in Microbiology, Vincent, Michael and Jo review the number of species on Earth, evidence that the 2010 Haitian cholera outbreak originated in Nepal, and how the gut microbiota influences the immune response to influenza virus infection of the lung.

Download TWiM #15 (43 MB, .mp3, 59 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Send your microbiology questions and comments to [email protected]

TWiM 14: Vomocytosis and microbial transistors

August 24, 2011

Hosts: Stanley Maloy, Margaret McFall-Ngai, Michael Schmidt, and Elio Schaechter

On episode #14 of the podcast This Week in Microbiology, Stanley, Margaret, Michael and Elio review how the fungus Cryptococcus escapes from macrophages, and electrical conductivity in nanowires formed by the bacterium Geobacter.

Download TWiM #14 (49 MB, .mp3, 68 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Nonlytic exocytosis of Cryptococccus (mBio)
Conductivity in microbial nanowire networks (Nature Nanotech)
Geobacter nanowires as transistors (North County Times)
Definitions: electrical conductivity, phonon, hysteresis
On Being the Right Size by JBS Haldane
The Biology of B Movie Monsters by Michael LaBarbera
Letters read on TWiM #14

Send your microbiology questions and comments to [email protected]

TWiM 13: Probiotics and inflammasomes: Telling good bacteria from the bad

August 10, 2011

Hosts: Stanley Maloy, Jo Handelsman, Michael Schmidt, and Elio Schaechter

On episode #13 of the podcast This Week in Microbiology, Stanley, Jo, Michael and Elio discuss how colonic microbial ecology and risk for colitis are regulated by an inflammasome, and amelioration of intestinal inflammation in mice by delivery of a probiotic-derived soluble protein to the colon.

Download TWiM #13 (42 MB, .mp3, 58 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Soluble protein ameliorates intestinal inflammation (JCI)
Inflammasome regulation of colonic microbial ecology and colitis risk (Cell)
Lactobacillus rhamnosis GG
p40 and p75 proteins from Lactobacillus casei (J Mol Micro Biotech)
Regulatory Oversight and Safety of Probiotic Use (pdf)
Letters read on TWiM #13

Send your microbiology questions and comments to [email protected]

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TWiM 22: Microbiology 911

Links for this episode:

TWiM 21: Symbiotic margheritas

Links for this episode:

TWiM 20: Facebook for bacteria

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TWiM 19: Your microbiome is what you eat

Links for this episode:

TWiM 18: Escherichia coli K-12, an emerging pathogen?

Links for this episode:

TWiM 17: Debugging endosymbiosis

Links for this episode:

TWiM 16: ICAAC Live

Links for this episode:

TWiM 15: Microbial long distance relationships

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TWiM 14: Vomocytosis and microbial transistors

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TWiM 13: Probiotics and inflammasomes: Telling good bacteria from the bad

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