This Week in Microbiology

TWiM 55: In the copper room

April 24, 2013

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter.

Vincent, Elio and Michael discuss the finding that copper surfaces reduce microbial burden and hospital-acquired infections in the intensive care unit.

Download TWiM #55 (58.5 MB .mp3, 85 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Copper reduces microbial burden on hospital surfaces (J Clin Micr)
Copper continuously limits bacterial on hospital bedrails (Inf Cont Hosp Epi)
Copper reduces healthcare-associated infection in the ICU (Inf Cont Hosp Epi)
Pathogens in the contaminated hospital environment (Inf Cont Hosp Epi)
Resistance on the surface (TWiM #47)
Letters read on TWiM 055

Send your microbiology questions and comments to [email protected]

TWiM 54: Dueling injectors and the microgenderome

April 10, 2013

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

Vincent, Elio, and Michael review how sex-dependent differences in the mouse microbiome regulate type I diabetes, and counterattack among bacteria.

Download TWiM #54 (53 MB .mp3, 72 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Send your microbiology questions and comments to [email protected]

TWiM 53: Live in Manchester

March 29, 2013

Hosts: Vincent Racaniello, Laura Piddock, David Harper, Kalin Vetsigian, and Paul Williams

Vincent, Laura, David, Kalin and Paul get together at the Society for General Microbiology meeting in Manchester, England to talk about next-generation approaches to antimicrobial therapy.

Download TWiM #53 (44 MB .mp3, 61 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

What is antibiotic action? (YouTube)
The crisis of no new antibiotics (Lancet)
Tackling antibiotic resistance (Nat Rev Micro)
Quorum sensing and social networking (J Roy Soc Interface)
Streptomyces interaction networks in soil (PLoS Biol)
What counters antibiotic resistance in nature? (Nat Chem Biol)
Clinical trials and bacteriophage therapy (J Mol Gen Med)

Send your microbiology questions and comments to [email protected]

TWiM 52: Clinical microbiology with Ellen Jo Baron

March 13, 2013

Hosts: Vincent Racaniello, Michael Schmidt, and Ellen Jo Baron

Vincent and Michael meet up with Ellen Jo Baron to talk about working in a clinical microbiology laboratory.

Download TWiM #52 (44 MB .mp3, 60 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

The excitement of clinical microbiology (STC)
Carbapenem-resistant Enterobacteriaceae (CDC)
Carbapenemases – Problem in waiting? (Curr Op Micro)
Ellen Jo Baron on Meet the Scientist #19

Send your microbiology questions and comments to [email protected]

TWiM 51: Cave science with Hazel Barton

February 27, 2013

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter, and Hazel Barton

Vincent, Michael, and Elio meet up with Hazel Barton to talk about cave microbiology.

Download TWiM #51 (38 MB .mp3, 79 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Antibiotic resistance in a cave microbiome (PLoS One)
Bacterial calcium carbonate precipitation in caves (Geomicro J)
Journey into Amazing Caves (IMAX)
In a cavern, in a canyon (STC)
Ancient bacterial resistome (STC)
Meet the Scientist #37 – Hazel Barton
Photo of Hazel Barton in Black Chasm Cavern by Dave Bunnell

Send your microbiology questions and comments to [email protected]

TWiM 50: These things aren’t even bacteria!

January 30, 2013

Carl Woese Hosts: Vincent Racaniello, Michael Schmidt, and Stanley Maloy

Vincent, Michael, and Stanley review the scientific career of Carl Woese.

Download TWiM #50 (47 MB .mp3, 64 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Solving the puzzle (MicrobeWorld Video)
Classification of methanogens by 16S rRNA (PNAS)
Ancient divergence among bacteria (J Mol Evol)
Intrepreting the phylogenetic tree (PNAS)
Phylogenetic structure of the prokaryotic domain (PNAS)
My kind of biology (Ann Rev Micro)
Tribute to Carl Woese (Tree of Life)
A manifesto for microbial genomics (Curr Biol)
Eisen analysis of ‘manifesto’ (Tree of Life)
Most important paper in microbiology? (Tree of Life)
Phylogenetic placement of Spirosomaceae (System. Appl. Microbiol)

Send your microbiology questions and comments to [email protected]

TWiM 49: Grape-like clusters

January 16, 2013

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

Vincent, Michael, and Elio discuss the HIV co-receptor CCR5 as a receptor for S. aureus leukotoxin ED, and the vineyard yeast microbiome.

Download TWiM #49 (53 MB .mp3, 73 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Transcript of this episode (Thanks, Frank!)
CCR5 is leukotoxin ED receptor (Nature)
A three-star pathogen (TWiM 42)
Vineyard yeast microbiome (PLoS One)
ARISA (AEM)
Herpes simplex virions bear Fc receptors (PLoS Biol)
Letters read on TWiM 049

Send your microbiology questions and comments to [email protected]

TWiM 48: It’s all about direction

January 3, 2013

Hosts: Vincent Racaniello, Michael Schmidt, and Jo Handelsman

Vincent, Michael, and Jo discuss how subtle gender bias of science faculty favors male students, and the relationship of invasive infection and antibody orientation at bacterial surfaces.

Download TWiM #48 (52 MB .mp3, 76 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Science faculty’s subtle gender biases (PNAS)
366 days: Nature’s 10
Antibody orentation and invasive infection (JEM)
Commentary on antibody and invasive infection (ScienceDaily)
Figure from Nordenfeldt et at. (JEM)
Letters read on TWiM 048

Send your microbiology questions and comments to [email protected]

TWiM 47: Resistance on the surface

December 19, 2012

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

Vincent, Michael, and Elio discuss the horizontal transfer of antibiotic resistance genes on metal surfaces, and using bacteriophage to reverse antibiotic resistance.

Download TWiM #47 (49 MB .mp3, 71 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Transcript of this episode (Thanks Raphael and Steve!)
Horizontal transfer of antibiotic resistance genes (mBio)
Why copper busts bacteria (Nanowerk)
Reversing antibiotic resistance (AEM)
How to reform a resistant bacterium (STC)
Letters read on TWiM 047

Send your microbiology questions and comments to [email protected]

TWiM 46: Spore!

December 5, 2012

Hosts: Vincent Racaniello,Michael Schmidt, Elio Schaechter and Jonathan Dworkin

Vincent, Michael, and Elio meet up with Jonathan Dworkin to discuss how bacteria form spores and how they return to vegetative growth.

Download TWiM #46 (50 MB .mp3, 70 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Transcript of this episode (Thanks, Frank Shinneman!)

Recent progress in B. subtilis sporulation (FEMS Micro Rev)
Pulsed feedback defers cell differentiation (PLoS Biol)
Built-in timer defers differentiation (PLoS Biol)
Spore formation in B. subtilis (YouTube)
Letters read on TWiM 046

Send your microbiology questions and comments to [email protected]

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TWiM 55: In the copper room

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TWiM 54: Dueling injectors and the microgenderome

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TWiM 53: Live in Manchester

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TWiM 52: Clinical microbiology with Ellen Jo Baron

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TWiM 51: Cave science with Hazel Barton

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TWiM 50: These things aren’t even bacteria!

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TWiM 49: Grape-like clusters

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TWiM 48: It’s all about direction

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TWiM 47: Resistance on the surface

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TWiM 46: Spore!

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