TWiV 959: Clinical update with Dr. Daniel Griffin

In his weekly clinical update Dr. Griffin discusses effectiveness of influenza vaccination of pregnant women for prevention of maternal and early infant Influenza-associated hospitalizations in South Africa, a multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes, single and 2-dose vaccinations with modified vaccinia Ankara-Bavarian Nordic induce durable B cell memory responses comparable to replicating smallpox vaccines, whether the risk of still and preterm birth is affected by the timing of symptomatic SARS-CoV-2 infection during pregnancy, medical masks versus N95 respirators for preventing COVID-19 among health care workers, alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants, real-world evidence of novel treatments for COVID-19 on mortality: a nationwide comparative cohort study of hospitalized patients in the 1^st, 2^nd, 3^rdand 4^th wave in the Netherlands, and effectiveness and safety of extended thromboprophylaxis in post-discharge patients with COVID-19.

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Download TWiV 959 (26 MB .mp3, 43 min)
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Links for this episode

• Effectiveness of Influenza vaccination in pregnant women (OFID) 6:23
• Multivalent nucleoside-modified mRNA vaccine against Influenza subtypes (Science) 7:56
• Single and 2-dose vaccinations with modified vaccinia Ankara-Bavarian Nordic (JID) 10:00
• Is the risk of still and preterm birth affected by the timing of symptomatic SARS-CoV-2 infection? (AJOG) 12:00
• Medical masks versus N95 respirators for preventing COVID-19 among health care workers (ACP) 14:24
• Bebtelovimab fact sheet for providers (FDA)
• Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants (bioRxiV) 26:59
• Paxlovid patient eligbiliity screening checklist (FDA)
• Real-world evidence of novel treatments for COVID-19 on mortality (OFID) 31:04
• Effectiveness and safety of extended thromboprophylaxis in post-discharge patients with COVID-19 (Thrombosis Research) 38:10
• Contribute to our MicrobeTV fundraiser at PWB 41:17
• Dr. Griffin’s treatment guide (pdf)
• Letters read on TWiV 959 41:34
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv