In COVID-19 clinical update #103, Daniel Griffin covers immunocompromised people, hospitalization of children, vaccine usage update, Omicron and cross-reactive neutralizing antibodies, reinfection prevents disease in hamsters, repeated infections with endemic coronaviruses, global burden of antimicrobial resistance, ivermectin not protective in hamsters, and Omicron evades therapeutic monoclonals.
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Links for this episode
- What does society owe immunocompromised people (Atlantic) 7:37
- Prevalence of immunosuppression in US (JAME) 6:25
- Hospitalizations of children (MMWR) 10:54
- Clinical considerations for vaccines (CDC) 13:33
- Sanofi seeks vaccine approval (Sanofi) 15:21
- Omicron triggers cross-reactive neutralization (medRxiv) 18:19
- Reinfection prevents disease in hamsters (Cell) 20:16
- Repeated infections with endemic CoV (J Inf Dis) 23:56
- Global burden of antimicrobial resistance (Lancet) 27:02
- Ivermectin not protective in hamsters (bioRxiv) 29:03
- Omicron evades therapeutic monoclonals (bioRxiv) 32:17
- Letters read on TWiV 870 37:03
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv
I have a friend who is a single mother with two children ages 8 and 12, all of are unvaccinated because the mother is “uncomfortable” with it – a typical antivax sentiment. It might be useful to break-out specifically the death rate in older children (i.e., eligible for vaccination) who are vaccinated vs unvaccinated so that these people can appreciate the additional additional risk they are exposing themselves and their families. I imagine if death rate is zero for vax’ed children, that might give people pause amid their distorted thought process.