TWiV 353: STING and the antiviral police

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler

The TWiVniacs discuss twenty-eight years of poliovirus shedding by an immunodeficient patient, and packaging of the innate cytoplasmic signaling molecule cyclic GMP-AMP in virus particles.

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Download TWiV 353 (73 MB .mp3, 101 min)
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Links for this episode

• 28 years of poliovirus shedding (PLoS Path) 36:50
• NOT a rare poliovirus (Wash Post) 44:35
• Ukraine polio outbreak (ProMedMail) 41:00
• Virus particle transfer of cGAMP (Science one, two) 47:50
• cGAS on TWiV 222 47:05
• Image credit
• Letters read on TWiV 353 6:30, 1:10:25

This episode is sponsored by ASMGAP 3:10

Timestamps by Jennifer. Thanks!

Weekly Science Picks 1:27:50

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Dickson – The Ph.D. Movie
Vincent – Ghostery

Listener Pick of the Week

Ramon – Children die
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Send your virology questions and comments to twiv@microbe.tv