Netcast TWiV 353: STING and the antiviral police September 6, 2015 Tagged as: agammaglobulinemia, cGAMP, cGAS, IFN, innate immunity, interferon, packaging, poliovirus, Sabin vaccine, shedding, STING, vaccine derived poliovirus, VDPV, viral, virology, virus, virus particle The TWiVniacs discuss twenty-eight years of poliovirus shedding by an immunodeficient patient, and packaging of the innate cytoplasmic signaling molecule cyclic GMP-AMP in virus particles.
