Vincent, Alan, Rich, and Judy Lieberman review the use of CD4 aptamer-siRNA chimeras to inhibit HIV transmission.
Vincent, Alan, and Dickson discuss the reduction in genome size of Mimivirus upon passage in amoeba, and analysis of the microbiome of honeybees.
Vincent meets up with Raul Andino in San Francisco to discuss the RNAi-based antiviral defense system of Drosophila, the fruit fly, and how it is antagonized by viruses.
The TWiV team speaks with Amit Kapoor and Ian Lipkin about how they discovered canine hepacivirus, and its implications for the origin and evolution of hepatitis C virus.
Retrovirologist Stephen Goff joins Vincent, Rich, and Alan for a discussion of recent papers on the retrovirus XMRV and its association with chronic fatigue syndrome and prostate cancer.
Vincent and guests Rachel Katzenellenbogen, Roger Hendrix, and Harmit Malik recorded TWiV #135 live at the 2011 ASM General Meeting in New Orleans, where they discussed transformation and oncogenesis by human papillomaviruses, the amazing collection of bacteriophages on the planet, and the evolution of genetic conflict between virus and host.
Vincent, Rich, Alan, and Dickson review noroviruses with Stephanie Karst, PhD.
Vincent, Rich, Alan, and Dickson discuss the cellular reservoir of HIV-1 with Kathleen Collins, MD, PhD.
Vincent, Rich, Alan, and Dickson speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about viral infections encountered in the emergency room.
Vincent, Alan, and Dickson chat with Brad Thompson, CEO of Oncolytics Biotech, about using reovirus to treat cancer.
The Hosts of TWiV
Vincent Racaniello, Ph.D.
Brianne Barker, Ph.D.
Rich Condit, Ph.D.
Alan Dove, Ph.D.
Daniel Griffin, M.D.,
Ph.D., CTropMed CTH
Angela Mingarelli, DVM
Jolene Ramsey, Ph.D.
Kathy Spindler, Ph.D.