TWiV explains the meaning of vaccine-derived poliovirus found in London sewage, risk of long COVID after infections with Delta or Omicron variants of SARS-CoV-2, and enhancers of innate immune signaling as broad-spectrum antivirals. Hosts: Vincent Racaniello,…
TWiV revisits Brazil’s rejection of Sputnik vaccine, examines influenza transmission via the air from the nasal epithelium of ferrets, and a history of accidental releases of polioviruses and their relevance for eradication of poliomyelitis.
Daniel Griffin provides a clinical report on COVID-19, then Amy joins us to discuss the 2020 Chemistry Nobel Prize for gene editing using CRISPR/Cas9, continuing circulation of poliovirus in Afghanistan, inborn errors of interferon in patients with severe COVID-19, and listener questions.
At Aarhus University in Denmark, Vincent speaks with Trine Mogensen, Søren Paludan, Ole Søgaard, and Madalina Carter-Timofte about their careers and their work on sensing herpesviral DNA, immunodeficiencies that predispose to severe viral infections, and the path to a cure for HIV/AIDS.
Vincent speaks with Julius about his long career in virology, including his crucial work as part of the team at the University of Pittsburgh that developed the Salk inactivated poliovirus vaccine.
Vincent and Rich discuss fruit fly viruses, one year without polio in Nigeria, and a permissive Marek’s disease viral vaccine that allows transmission of virulent viruses.
The TWiV team discusses the possible association of the respiratory pathogen enterovirus D68 with neurological disease.
Vincent meets up with Peter L. Salk to talk about development of the first poliovaccine, eradication of poliomyelitis, and Jonas Salk’s 100th birth anniversary.
Vincent and Alan converse about making published science accessible to everyone, global eradication of poliomyelitis, and whether a plant virus can cause disease in humans.
Vincent, Alan, and Rich discuss ten compelling virology stories of 2009.