B cell | This Week in Virology

A TWiV trio reveal the isolation of novel paramyxoviruses from rodents and bats in Arizona, and isolation of naive B cells from seronegative donors that produce germline encoded antibodies which engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses from bats.

TWiV 620: Antibodies and T cells in COVID-19 patients

May 29, 2020
Tagged as: antibody, B cell, CD4, CD8, COVID-19, neutralizing antibody, SARS-CoV-2, T cell, t cell epitope, viral, virology, virus, viruses

Jon Yewdell returns to explain studies on detection of antibodies and T cell epitopes in patients who have recovered from COVID-19.

TWiV 602: Coronavirus immunology with Stanley Perlman

April 16, 2020
Tagged as: antibody, B cell, coronavirus, CoV, COVID-19, immunology, MERS-CoV, SARS-CoV, SARS-CoV-2, T cell, viral, virology, virus, viruses

Stanley Perlman joins TWiV to discuss immune responses to coronaviruses, including seasonal CoV, MERS, SARS, and SARS-CoV-2, including prospects for a vaccine.

TWiV 597: A lot of immunology and some COVID-19 with Jon Yewdell

April 3, 2020
Tagged as: antibody, B cell, coronavirus, COVID-19, immunology, interferon, SARS-CoV-2, T cell, viral, virology, virus, viruses

Immunologist Jon Yewdell joins Vincent and Rich to discuss immune responses in the context of infection with SARS-CoV-2.

The TWiVonauts review how the weather affects West Nile virus disease in the US, benefit of B cell depletion for ME/CFS patients, and an autoimmune reaction induced by influenza virus vaccine that leads to narcolepsy.

The TWiVbolans discuss the finding that human noroviruses, major causes of gastroenteritis, can for the first time be propagated in B cell cultures, with the help of enteric bacteria.

Netcast

TWiV 161: Concerto in B

December 11, 2011
Tagged as: antibody, B cell, germinal center, immunology, lymph node, somatic mutation, two photon microscopy, VDJ rearrangement, viral, virology, virus

Vincent, Rich, Alan and Gabriel review the production of antibodies by B cells, and how high affinity antibodies are selected in the germinal centers of lymph nodes.

Tag: B cell

TWiV 821: Public clonotype #1

TWiV 620: Antibodies and T cells in COVID-19 patients

TWiV 602: Coronavirus immunology with Stanley Perlman

TWiV 597: A lot of immunology and some COVID-19 with Jon Yewdell

TWiV 345: How a vaccine got the nod

TWiV 312: She sells B cells

TWiV 161: Concerto in B

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Inside a BSL-4 laboratory