The TWiV team discusses Medusavirus, isolated from a hot spring in Japan, and induction of hallmarks of neurodegeneration by recurrent herpes simplex virus 1 infection of mice.

The TWiV hosts review persistence of Ebola virus after the end of the Liberian outbreak, and the potential role of two herpesviruses in the pathogenesis of Alzheimer’s disease.

Vincent and Dick continue virology 101 with a discussion of virus entry into cells, then answer reader email on colony collapse disorder and viruses that confer a benefit to their host.