The TWiVanguardians take on Bodo saltans virus, a leviathan which infects an abundant flagellated eukaryote in Earth’s waters.
Anthony writes: HMS Beagle set sail on 27 December: https://www.facebook.com/theroyalsociety/posts/1767879073244620 The Royal Society added 4 new photos. The epic HMS Beagle voyage that helped shape the scientific theories of Charles Darwin, set sail #onthisday in…
The Fellowship of the Virus discuss enhancement of dengue disease in humans: the contribution of antibody concentration and increased binding to Fc receptors.
Joseph writes: Greetings again TWIV docs, As someone who worked on identifying physiologically relevant CD8+ T cell epitopes for potential dengue vaccines, thanks for covering the latest on Dengvaxia. The background scuttlebutt in our…
Ben Padman writes: Hi there, I heard your questions about the CLEM (Correlative Light Electron Microscopy) experiment from the transcytosis paper and wanted to clear up a few things: 1) I acquired the optical and…
The TWiVerinos discuss restriction of dengue virus vaccine by Sanofi, and data which suggest that Dengvaxia causes enhanced disease in previously uninfected recipients.
Islam writes: I just wanted to say thank you for recording a TWiV episode on the Friday after Thanksgiving when pretty much everybody else was holidaying. Thanks for making my Mondays wonderful! By the way,…
The TWiVians present an imported case of yellow fever in New York City, and explain how a dengue virus subgenomic RNA disrupts immunity in mosquito salivary glands to increase virus replication
Brianne joins the TWiVMasters to explain how mutations in genes encoding RNA polymerase III predispose children to severe varicella, and detection of an RNA virus by a DNA sensor.
Sharon and Scott return to TWiV for a Zika virus update, including their work on viral evolution and spread, and whether pre-existing immunity to dengue virus enhances pathogenesis.