TWiV 458: Saliva of the fittest

The TWiVians present an imported case of yellow fever in New York City, and explain how a dengue virus subgenomic RNA disrupts immunity in mosquito salivary glands to increase virus replication.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

Click arrow to play
Download TWiV 458 (72 MB .mp3, 119 min)
Subscribe (free): iTunes, RSS, email

Become a patron of TWiV!

Links for this episode

• ASM Conference on Viral Manipulation of Nuclear Processes
• Roger W. Hendrix, 74 (Pittsburgh Post-Gazette)
• Roger Hendrix video on TWiV #135
• Yellow fever in traveler returning from Peru (MMWR)
• Dengue subgenomic RNA in mosquito salivary gland (PLoS Path)
• Image credit
• Letters read on TWiV 458

This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

Weekly Science Picks

Kathy – Antibody validation Editorial Asilomar meeting report
Dickson – Despommierphotoart.com
Alan – NOAA Hurricane Hunters
Rich – Awakenings by Oliver Sacks (encephalitis lethargica)
Vincent – Goodnight Lab by Chris Ferrie

Listener Picks

Pete – Change Agent by Daniel Suarez
Paul – Pasteur’s Gambit by Stephen Dando-Collins
Maureen – Discovery Documentary First in Human

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv