TWiV 456: Be careful of canons

August 26, 2017

dengue-cGASBrianne joins the TWiVMasters to explain how mutations in genes encoding RNA polymerase III predispose children to severe varicella, and detection of an RNA virus by a DNA sensor.

Hosts: Vincent Racaniello and Rich Condit

Guest: Brianne Barker

Click arrow to play
Download TWiV 456 (75 MB .mp3, 124 min)
Subscribe (free): iTunesRSSemail

Become a patron of TWiV!

Links for this episode

This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at

Weekly Science Picks

Brianne – Up-Goer Five Challenge (related to Thing Explainer)
Rich – The Farthest: Voyager in Space and Vipassana Momma: Science
Vincent – Episode of Revisionist History: The Basement Tapes

Listener Pick

Jennie – What Piece of Lab Equipment Are You?

Intro music is by Ronald Jenkees.

Send your virology questions and comments to

Leave a Reply

Your email address will not be published. Required fields are marked *

3 comments on “TWiV 456: Be careful of canons