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Tag: parasitism

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TWiP 119: A kinder and gentler case

  • October 25, 2016
  • Tagged as: Dientamoeba fragilis, eosinophilia, genome, HIV-1, infection, integrase, integration, parasite, parasitism, reverse transcriptase, Schistosoma mansoni
TWiP

Vincent and Daniel solve the case of the Family with Eosinophilia, and discuss HIV-1 infection and genome integration in the blood fluke Schistosoma mansoni.

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  • Episodes

TWiP 118: Crispr capers with Toxoplasma

  • October 6, 2016
  • Tagged as: apicomplexan, Cas9, CRISPR, essential gene, gene editing, guinea, malaria, parasite, parasitism, Plasmodium knowlsei, recurrent fever, toxoplasma
TWiP

The TWiPinella solve the case of the Woman from Guinea, and describe the use of CRISPR/Cas9 to identify essential apicomplexan genes.

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  • Episodes

TWiP 117: Parasitic puzzles

  • September 26, 2016
  • Tagged as: cutaneous leishmaniasis, dsRNA, IL-17A, interferon gamma, Leishmania mexicana, leishmaniasis, leishmaniavirus, metastatic leishmaniasis, parasite, parasitism
TWiP

The parasite prophets solve the case of the Thai Man with Abdominal Distention, and discuss the finding that metastatic leishmaniasis dependent on a virus can be prevented by blocking IL-17A.

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  • Episodes

TWiP 116: One drug to rule them all

  • September 10, 2016
  • Tagged as: Chagas disease, inhibitor, kinetoplastid, leishmania, parasite, parasitism, proteasome, sleeping sickness, Trypanosoma brucei, Trypanosoma cruzi
TWiP

The TWiPtoids solve the case of the Thai Fisherman with Chronic Diarrhea, and reveal a potential new drug for treatment of leishmaniasis, Chagas diseases, and sleeping sickness.

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  • Episodes

TWiP 115: The Cuscuta Factor

  • August 27, 2016
  • Tagged as: amoeba, brain eating amoeba, Cuscuta, dodder, eukaryote, holoparasite, Naegleria fowleri, parasite, parasitism, primary amoebic meningoencephalitis, stem holoparasite, tomato
TWiP

The TWiPlets solve the sad case of the Boy Who Went Swimming, and explain why the tomato is resistant to the plant parasite Cuscuta.

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  • Episodes

TWiP 114: Plant potions perturb Plasmodium

  • August 12, 2016
  • Tagged as: Anopheles, case study, eukaryotic, malaria, mosquito, parasite, parasitism, plant sap, Plasmodium falciparum, sugar source, trichomonas vaginalis
TWiP

The TWiP troika solve the case of the Female from the Bronx, and reveal how feeding on different plants affects mosquito capacity to transmit malaria.

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  • Episodes

TWiP 113: Flying pigs

  • July 23, 2016
  • Tagged as: Eimeria tenella, neurocystercercosis, parasite, parasitism, pork tapeworm, Taenia solium, toxoplasma, toxoplasmosis, transgenic, vaccine
TWiP

The TWiP ternion solve the case of the Man from Mexico, and discuss a transgenic toxoplasma vaccine for chickens using Eimeria tenella.

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  • Episodes

TWiP 112: A NOD to a tricky helminth

  • June 25, 2016
  • Tagged as: Bacterioides, Clostridium, Crohn's disease, helminth, inflammatory bowel disease, microbiota, Nod2, parasite, parasitism, Trichuris muris, type 2 immunity
TWiP

The TWiP trio solve the case of the Woman from Washington Heights, and reveal how helminth infection protects mice deficient in the Crohn’s disease gene NOD2 from intestinal disease by inhibiting colonization with an inflammatory bacterial species.

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  • Episodes

TWiP 111: Bug bites

  • June 3, 2016
  • Tagged as: bed bug, bug, c-myc, Cimex lectularius, ectoparasite, effector protein, MYR1, parasite, parasitism, parasitophorous vacuole, protozoan, rhoptry, toxoplasma gondii
TWiP

The TWiP trio solve the case of the bug bites all in a row, and talk about a secreted Toxoplasma protein that is central to the parasite’s manipulation of host cells.

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  • Episodes

TWiP 110: Malaria at the Bronx Zoo

  • May 21, 2016
  • Tagged as: avian malaria, Bronx Zoo, malaria, parasite, parasitism, penguin, Wildlife Conservation Society
TWiP

The TWiP trio visit the Bronx Zoo where Paul solves the case of the Four Year Old with Pulmonary Edema, and talks about his career as the Chief Veterinarian and Director of the Zoological Health program for the Wildlife Conservation Society.

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Christina Naula, Ph.D.


Daniel Griffin, M.D.,

Vincent Racaniello, Ph.D.


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