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Tag: Trypanosoma brucei

  • Episodes

TWiP 164: Surf n’ perf

  • January 12, 2019
  • Tagged as: endosymbiont, leishmaniasis, parasite, parasitism, parasitology, Sodalis glossinidius, symbiosis, Trypanosoma brucei, tsetse fly, Wigglesworthia, Wigglesworthia glossinidia

The TWiP legends solve the case of Surfer Sans Septum, and discuss how two symbiotic bacteria in the tsetse fly might allow colonization with Trypanosoma brucei.

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  • Episodes

TWiP 130: Paige Turner

  • April 1, 2017
  • Tagged as: AIDS, ESCRT, exosomes, parasite, parasitism, social motility, spliced leader RNA, trans splicing, Trypanosoma brucei
TWiP

The TWiPniks solve the case of the Man With AIDS, and explore how secretion of extracellular vesicles influences the social motility of Trypanosoma brucei.

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  • Episodes

TWiP 116: One drug to rule them all

  • September 10, 2016
  • Tagged as: Chagas disease, inhibitor, kinetoplastid, leishmania, parasite, parasitism, proteasome, sleeping sickness, Trypanosoma brucei, Trypanosoma cruzi
TWiP

The TWiPtoids solve the case of the Thai Fisherman with Chronic Diarrhea, and reveal a potential new drug for treatment of leishmaniasis, Chagas diseases, and sleeping sickness.

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  • Episodes

TWiP 68: Sex and the single trypanosome

  • March 7, 2014
  • Tagged as: gametes, meiosis, parasite, parasitism, podcast, sexual reproduction, Trypanosoma brucei, twip

Vincent, Dickson, and Sagi discuss evidence that the pathogen Trypanosoma brucei undergoes meiosis and sexual reproduction.

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  • Episodes

TWiP 66: A nitrile warhead for Chagas disease

  • February 8, 2014
  • Tagged as: Chagas disease, cruzipain, cysteine protease inhibitor, parasite, parasitism, Trypanosoma brucei, Trypanosoma cruzi

Vincent and Dickson discuss reversible inhibitors of cruzipain as new drugs for treating Chagas disease.

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  • Episodes

TWiP 43: Two remarkable host-parasite conflicts

  • August 23, 2012
  • Tagged as: adenylate cyclase, innate immunity, malaria, miRNA, parasite, parasitism, Plasmodium falciparum, sickle cell, Trypanosoma brucei, trypanosome

Vincent and Dickson review how sickle cell microRNAs contribute to malaria resistance, and inhibition of innate immune responses by an enzyme from trypanosomes.

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