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Tag: malaria

  • Episodes

TWiP 167: The constipated mathematician

  • February 27, 2019
  • Tagged as: capillary, endothelium, Giardia lamblia, giardiasis, glycocalyx, malaria, nitric oxide, parasite, parasitism, parasitology, steatorrhea

The Tremendous Trio solve the case of the Woman With Steatorrhea, and reveal breakdown of the glycocalyx associated with severe and fatal malaria.

1 Reply
  • Episodes

TWiP 165: The sound of crackles

  • January 26, 2019
  • Tagged as: B-1 cells, crackles, cytokines, extracellular vesicles, Leishmania amazonensis, macrophages, malaria, parasite, parasitism, parasitology

The TWiP team solve the case of the Four Year Old with Fever, Headache, and Cough, and discuss the release of extracellular vesicles from Leishmania amazonensis that manipulate the host immune response.

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  • Episodes

TWiP 152: A range of rads

  • May 26, 2018
  • Tagged as: circumsporozoite antigen, Giardia, malaria, monoclonal antibody, parasite, parasitism, parasitology, Plasmodium berghei, Plasmodium falciparum, steatorrhea

The TWiP peeps solve the case of the Panamanian Mother with Steatorrhea, and reveal new monoclonal antibodies that effectively block malarial infection.

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  • Episodes

TWiP 151: Indiscriminate bulk feeders

  • May 2, 2018
  • Tagged as: Ascaris, blood, bloodsucking, Falciparum, helminth, hookworm, malaria, parasite, parasitism, parasitology, resource competition, scabies

The Podfessors solve the case of the Itchy Child from Panama, and discuss competition for blood in human malaria-helminth co-infections.

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  • Episodes

TWiP 146: Thus misspake Despommier

  • January 31, 2018
  • Tagged as: case study, diarrhea, Fasciolopsis buski, iron, malaria, parasite, parasitism, Plasmodium vivax, receptor, reticulocyte, transferrin, transferrin receptor 1

The TWIPniks solve the case of the Man With Diarrhea and 100 Micron Objects In Stool, and discuss the reticulocyte receptor for Plasmodium vivax.

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  • Episodes

TWiP 143: There’s a lot of worms out there

  • November 28, 2017
  • Tagged as: anemia, aspartate protease, eosinophila, malaria, parasite, parasitism, plasmepsin, Plasmodium falciparum, red blood cell egress, red blood cell invasion, rhoptry, ring form, worm

The TWiPians solve the case of the Woman With Anemia, Eosinophila, and a Worm in Her Intestine, and discuss a study on the function and druggability of two malarial aspartate proteases.

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  • Episodes

TWiP 125: Third time’s a charm

  • January 21, 2017
  • Tagged as: Anopheles, malaria, mosquito, parasite, parasitism, parasitology, Plasmodium falciparum, sporozoite, vaccine
TWiP

The TWiPonderers solve the case of the Timber Worker with Severe Shaking Chills, and describe an experimental malaria vaccine comprising attenuated sporozoites produced by genetic engineering.

1 Reply
  • Episodes

TWiP 123: What we know is confusing

  • December 20, 2016
  • Tagged as: case study, complement, cytoadhesion, erythrocyte, malaria, myiasis, parasite, parasitism, parasitology, Plasmodium falciparum
TWiP

The TWiPanorama solve the case of the Dutch Woman with Wormy Objects in Her Stool, dissect a study on cytoadhesion of malaria infected red blood cells, and introduce Parasitology Superheroes.

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  • Episodes

TWiP 118: Crispr capers with Toxoplasma

  • October 6, 2016
  • Tagged as: apicomplexan, Cas9, CRISPR, essential gene, gene editing, guinea, malaria, parasite, parasitism, Plasmodium knowlsei, recurrent fever, toxoplasma
TWiP

The TWiPinella solve the case of the Woman from Guinea, and describe the use of CRISPR/Cas9 to identify essential apicomplexan genes.

1 Reply
  • Episodes

TWiP 114: Plant potions perturb Plasmodium

  • August 12, 2016
  • Tagged as: Anopheles, case study, eukaryotic, malaria, mosquito, parasite, parasitism, plant sap, Plasmodium falciparum, sugar source, trichomonas vaginalis
TWiP

The TWiP troika solve the case of the Female from the Bronx, and reveal how feeding on different plants affects mosquito capacity to transmit malaria.

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Christina Naula, Ph.D.


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