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Tag: malaria

  • Episodes

TWiP 50: Antagonism in the mosquito midgut

  • February 16, 2013
  • Tagged as: complement, factor H, lysis, malaria, mosquito, parasite, parasitism, Plasmodium

Vincent and Dickson reveal how malaria parasites avoid lysis by complement in the mosquito.

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  • Episodes

TWiP 46: Malaria gets the (zinc) finger

  • October 16, 2012
  • Tagged as: gene editing, gene replacement, malaria, mutagenesis, parasite, parasitism, Plasmodium falciparum, zinc finger nuclease

Vincent and Dickson meet with Judith Straimer and Marcus Lee to discuss their method for site-specific genome editing in Plasmodium falciparum using zinc finger nucleases.

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  • Episodes

TWiP 43: Two remarkable host-parasite conflicts

  • August 23, 2012
  • Tagged as: adenylate cyclase, innate immunity, malaria, miRNA, parasite, parasitism, Plasmodium falciparum, sickle cell, Trypanosoma brucei, trypanosome

Vincent and Dickson review how sickle cell microRNAs contribute to malaria resistance, and inhibition of innate immune responses by an enzyme from trypanosomes.

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  • Episodes

TWiP 35: Malaria control with David Fidock

  • January 13, 2012
  • Tagged as: artemisinin, chloroquine, drug resistance, malaria, parasite, parasitism, Plasmodium

Vincent and Dickson discuss control of malaria with their Columbia University colleague David Fidock.

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  • Episodes

TWiP 34: Up against the Wolbachia

  • December 13, 2011
  • Tagged as: aedes aegypti, Anopheles, filaria, malaria, mosquito, parasite, parasitism, Plasmodium, symbiosis, wolbachia

Vincent and Dickson discuss control of malaria and filariasis with the bacterial endosymbiont Wolbachia.

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  • Episodes

TWiP 31 – A malaria vaccine

  • October 21, 2011
  • Tagged as: circumsporozoite, malaria, parasite, parasitism, twip, vaccine
p. falciparum life cycle

Vincent and Dickson discuss the promising results of a phase III trial of a malaria vaccine in African children.

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  • Episodes

TWiP 28: Medical entomology with Robert W. Gwadz

  • July 26, 2011
  • Tagged as: malaria, medical entomology, mosquito, parasite, parasitism, podcast, twip, vector

Vincent and Dickson discuss medical entomology with Robert W. Gwadz, Assistant Chief of the Laboratory of Malaria and Vector Research at NIAID.

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  • Episodes

TWiP 11: One times three million

  • June 2, 2010
  • Tagged as: malaria, parasite, parasitism, pathogenesis

Vincent and Dickson continue their discussion of malaria, with emphasis on clinical aspects of the disease.

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  • Episodes

TWiP 10: Plasmodium life cycle

  • May 19, 2010
  • Tagged as: life cycle, malaria, parasite, parasitism, Plasmodium

Vincent and Dickson trace the life cycle of Plasmodium in a mosquito and in a human host.

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  • Episodes

TWiP 9: Mala aria

  • May 6, 2010
  • Tagged as: malaria, parasite, parasitism, Plasmodium, protozoa

Vincent and Dickson move on to protozoan parasites with a discussion of the early history of malaria.

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