Tag: leishmania

• This Week in Parasitism

TWiP 251: Case of the facial ulcer

• January 17, 2025
• Tagged as: cutaneous leishmaniasis, facial ulcer, leishmania, parasite, parasitism, parasitology, sandfly

TWiP solves the case of the woman who went to Belize and notices a lesion on her face, and presents a new clinical case for you to solve. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula…

• Episodes

TWiP 201: Tiny and hairy

• December 7, 2021
• Tagged as: animal reservoir, disease eradication, leishmania, parasite, parasitism, parasitology, Phlebotomus, ring enhancing lesions, sandfly, toxoplasma, toxoplasmosis

The TWiP team solves the case of the Man with a Cat and Ring Enhancing Lesions, and discuss domestic mammals as reservoirs for Leishmania donovani on the Indian subcontinent.

• Episodes

TWiP 150: Fast food

• April 19, 2018
• Tagged as: Callinectes sapidus, crab, Eurypanopeus depressus, invasive species, leishmania, Loxothylacus panopaei, native predator, parasite, parasitism, parasitology

The TWiPers solve the case of the Panamanian Man With Leg Ulcer, and describe how a crab predator preferentially feeds on parasite infected prey – even though the parasite makes them faster!

• Episodes

TWiP 138: Telmophages and the skin parasite landscape

• September 6, 2017
• Tagged as: hair lice, infectiousness, leishmania, nit, parasite, parasitism, Pediculus humanus capitis, sandfly, skin, skin parasite landscape, solenophage, telmophage

The TWiPsters solve the case of the Child from DR with Poppy Seed Sized Things On His Head Hair Shafts, and reveal how the skin parasite landscape determines the infectiousness of Leishmania.

• Episodes

TWiP 137: An aberrant encounter

• August 12, 2017
• Tagged as: cutaneous leishmaniasis, cysticercosis, dysbiosis, inflammation, leishmania, microbiome, parasite, parasitism, pork tapeworm, Taenia solium

The TWiPtoids solve the case of the Man from India with a Neck Lump, and explore the role of a transmissible dysbiotic skin microbiome in inflammation during cutaneous leishmaniasis.

• Episodes

TWiP 136: Daniel throws a softball

• July 11, 2017
• Tagged as: Carter center, dracunculiasis, Dracunculus medinensis, eradication, Guinea worm, inducible nitric oxide synthase, inflammatory monocytes, iNOS, leishmania, monocytes, parasite, parasitism, reactive oxygen species, sand fly

The TWiP Titans solve the case of the Man from Queens with a Blister Burster, and explain the role of inflammatory monocytes during Leishmania infection of the skin.

• Episodes

TWiP 127: Kava not Cava

• February 15, 2017
• Tagged as: amebiasis, case study, gut microbiome, leishmania, Lutzomyia, parasite, parasitism, sandfly

The TWiPsters solve the case of the Peace Corps Volunteer with a Liver Lesion, and discuss the dependence of Leishmania survival on the gut microbiome of the sandfly.

• Episodes

TWiP 126: A virus walks into a parasite

• February 4, 2017
• Tagged as: dsRNA virus, leishmania, leishmaniasis, leishmaniavirus, parasite, parasitism, T cells, vaccine

The TWiP Trinity solve the case of the Peace Corps volunteer with diarrhea, and reveal how immunizing against a virus ameliorates exacerbated leishmaniasis.

• Episodes

TWiP 122: If the thunder don’t get you, the lightning will

• December 6, 2016
• Tagged as: allbendazole, cytokine, deworming, helminth, hookworm, immune hyporesponsiveness, immunosuppression, leishmania, mucocutaneous leishmaniasis, parasite, parasitism, sandfly, soil transmitted helminth

The TWiPniks docs solve the case of the Female from Peru with Epistaxis, and discuss the effect of community deworming on immunosuppression.

• Episodes

TWiP 116: One drug to rule them all

• September 10, 2016
• Tagged as: Chagas disease, inhibitor, kinetoplastid, leishmania, parasite, parasitism, proteasome, sleeping sickness, Trypanosoma brucei, Trypanosoma cruzi

The TWiPtoids solve the case of the Thai Fisherman with Chronic Diarrhea, and reveal a potential new drug for treatment of leishmaniasis, Chagas diseases, and sleeping sickness.