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Category: Episodes

  • Episodes

TWiP 148: Weep and sweep

  • March 7, 2018
  • Tagged as: B1 cell, B2 cell, goblet cell, hookworm, IgE, mast cell, mucus, parasite, parasitism, parasitology, Stronglyoides

The TWiP-tologists solve the case of the Child in South America With Belly Pain, and reveal how B1 cell IgE blocks parasite clearance by inhibiting mast cell activation by B2 cell IgE.

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  • Episodes

TWiP 147: The savvy physician tests the tissue

  • February 24, 2018
  • Tagged as: Balyisascaris procyonis, Costa Rica, cutaneous leishmaniasis, foot ulcer, parasite, parasitism, raccoon roundworm, Rattus rattus, rodent, transmission

The three amigos of parasitology solve the case of the New York Lawyer With A Foot Ulcer, and discuss a survey of rodents for the raccoon roundworm in California.

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  • Episodes

TWiP 146: Thus misspake Despommier

  • January 31, 2018
  • Tagged as: case study, diarrhea, Fasciolopsis buski, iron, malaria, parasite, parasitism, Plasmodium vivax, receptor, reticulocyte, transferrin, transferrin receptor 1

The TWIPniks solve the case of the Man With Diarrhea and 100 Micron Objects In Stool, and discuss the reticulocyte receptor for Plasmodium vivax.

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  • Episodes

TWiP 145: Is it excreted or secreted?

  • January 17, 2018
  • Tagged as: anisakis, Diphyllobothrium, excreted proteins, Giardia, intestinal epithelial cells, parasite, parasitism, salmon, secreted proteins, secretome, vitamin B12

The Estimados Profesores of TWIP solve the case of the Man With Motile Objects, and reveal the secreted and excreted proteins of Giardia parasites.

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  • Episodes

TWiP 144: A blood-free snip

  • December 14, 2017
  • Tagged as: excretedproteins, ivermectin, mass spectometry, nurse cell, onchocerca volvulus, parasite, parasitism, river blindness, secreted proteins, Trichinella pseudospiralis

The TWiPtomaniacs solve the case of the Boy With Visual Disturbances and Itching, and discuss identifying secreted and excreted proteins of Trichinella parasites.

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  • Episodes

TWiP 143: There’s a lot of worms out there

  • November 28, 2017
  • Tagged as: anemia, aspartate protease, eosinophila, malaria, parasite, parasitism, plasmepsin, Plasmodium falciparum, red blood cell egress, red blood cell invasion, rhoptry, ring form, worm

The TWiPians solve the case of the Woman With Anemia, Eosinophila, and a Worm in Her Intestine, and discuss a study on the function and druggability of two malarial aspartate proteases.

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  • Episodes

TWiP 142: Just a virus, go home

  • November 17, 2017
  • Tagged as: acidification, ApoL1, apolipoprotein, apoptosis, endosome, mitochondria, parasite, parasitism, trypanosome

The TWiPsids solve the case of the Guatemalan Positive for Rhinovirus, and reveal how to kill all African trypanosomes with a primate apolipoprotein.

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  • Episodes

TWiP 141: Paratransgenesis

  • October 31, 2017
  • Tagged as: Cordylobia anthropophaga, gene drive, midgut, myiasis, Operation Sea Spray, parasite, parasitism, Plasmodium, Serratia marcescens, symbiosis, tumbu fly

The TWiP Wataalamu solve the case of the One Year Old From Kenya With Moving  Skin Lesions, and describe how to make mosquitoes refractory to Plasmodium with engineered symbiotic bacteria.

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  • Episodes

TWiP 140: Blasting Blastocystis

  • October 17, 2017
  • Tagged as: anaerobic, blast, Blastocystis, eosinophilia, eukaryote, genome, parasite, parasitism, stramenopile

The triple TWiP solve the case of the Peace Corp Veteran with Eosinophilia, and discuss the genome sequence of the hyper-prevalent parasitic eukaryote Blastocystis.

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  • Episodes

TWiP 139: Eggsactly, ova and ova

  • September 21, 2017
  • Tagged as: Baylisascaris procyonis, granuloma formation, iNOS, mitochondria, nitric oxide, nitric oxide synthase, Norway rat, ocular larva migrans, parasite, parasitism, rat, Schistosoma japonicum, schistosomiasis

The TWiPwalas solve the case of the Woman with a Worm in Her Eye, and discuss the role of nitric oxide in the resistance of rats to Schistosoma japonicum.

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