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Category: Episodes

  • Episodes

TWiP 168: Kleptoparasitism and the stercoraceous souvenir

  • March 27, 2019
  • Tagged as: constipation, Entamoeba hartmanni, goblet cell, Gαo, Gβ1γ13, Ip3r2, parasite, parasitism, Trichinella, tuft cell, weep and sweep, α-gustducin

The Giardians of the Galaxy solve the case of the Woman With a Colonic Stowaway from Hispaniola, and discuss activation of intestinal tuft cells by Trichinella spiralis.

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  • Episodes

TWiP 167: The constipated mathematician

  • February 27, 2019
  • Tagged as: capillary, endothelium, Giardia lamblia, giardiasis, glycocalyx, malaria, nitric oxide, parasite, parasitism, parasitology, steatorrhea

The Tremendous Trio solve the case of the Woman With Steatorrhea, and reveal breakdown of the glycocalyx associated with severe and fatal malaria.

1 Reply
  • Episodes

TWiP 166: From remote locations

  • February 16, 2019
  • Tagged as: B1 cells, Chagas disease, elephantiasis, parasite, parasitism, parasitology, Trypanosoma cruzi, Wuchereria bancrofti

The Podfessors solve the case of the Teenager With Swollen Scrotum, and continue the story arc of Daniel’s favorite cells, B-1 cells, and their association with protective immune responses in human Chagas disease.

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  • Episodes

TWiP 165: The sound of crackles

  • January 26, 2019
  • Tagged as: B-1 cells, crackles, cytokines, extracellular vesicles, Leishmania amazonensis, macrophages, malaria, parasite, parasitism, parasitology

The TWiP team solve the case of the Four Year Old with Fever, Headache, and Cough, and discuss the release of extracellular vesicles from Leishmania amazonensis that manipulate the host immune response.

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  • Episodes

TWiP 164: Surf n’ perf

  • January 12, 2019
  • Tagged as: endosymbiont, leishmaniasis, parasite, parasitism, parasitology, Sodalis glossinidius, symbiosis, Trypanosoma brucei, tsetse fly, Wigglesworthia, Wigglesworthia glossinidia

The TWiP legends solve the case of Surfer Sans Septum, and discuss how two symbiotic bacteria in the tsetse fly might allow colonization with Trypanosoma brucei.

2 Replies
  • Episodes

TWiP 163: Trout and parasites

  • December 29, 2018
  • Tagged as: bony fish, halzoun, Ich, Ichthyophthirius multifiliis, IgT, immunoglobulins, NALT, nasal-associated lymphoid tissue, olfactory organ, Oncorhynchus mykiss, parasite, parasitism, raw meat, toxoplasma gondii, toxoplasmosis, trout

The doctors of awesome solve the case of the Woman Who Visited Lebanon, and reveal that immunoglobulins protect the olfactory organ of trout against infection with the Ich parasite.

3 Replies
  • Episodes

TWiP 162: That swollen parcel of dropsies

  • November 21, 2018
  • Tagged as: Chagas disease, Dientamoeba fragilis, gastrointestinal illness, parasite, parasitism, parasitology, Trypanosoma cruzi, trypanosome

The TWiP professors solve the case of the Baby With Pericardial Effusion, and discuss whether the flagellate without a flagella, Dientamoeba fragilis, causes human illness.

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  • Episodes

TWiP 161: All I need is a bit of skin

  • November 10, 2018
  • Tagged as: antigenic variation, Chagas disease, chromatin, chromosome conformation capture, Hi-C, histone, nucleosome, parasite, parasitism, parasitology, Trypanosoma cruzi, trypanosome, variant surface glycoprotein

The TWiPsters solve the case of the Brazilian Immigrant With Heart Problems, and describe how genome organization controls trypanosome antigenic variation.

1 Reply
  • Episodes

TWiP 160: Toddy tappers

  • October 10, 2018
  • Tagged as: amoeba, Chad, date palm wine, dog, dracunculiasis, Dracunculus medinensis, Entamoeba histolytica, Guinea worm, Guinea worm disease, parasite, parasitism, parasitology, toddy tapper

The TWiPlets solve the case of the Electrician from Tamil Nadu with a Liver Mass, and reveal that dogs and humans share a common Chadian Guinea worm.

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  • Episodes

TWiP 159: Loa and Loa but not gone

  • September 28, 2018
  • Tagged as: community treatment, ivermectin, loa loa, loiasis, microfilariae, onchocerciasis, parasite, parasitism, parasitology

The TWiP triptych solve the case of the 9/11 Survivor infested with parasites, and discuss the effect of community ivermectin treatment for onchocerciasis on Loa loa infections.

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