Infectious Disease physician Jake Scott joins TWiV to provide a west coast clinical perspective on the evolution of the COVID-19 pandemic with respect to the impact of vaccines, antivirals, variants of concern and mortality.
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler
Guest: Jake Scott
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Download TWiV 952 (63 MB .mp3, 104 min)
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Links for this episode
- Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV
- Omicron variant reproduction ex vivo (Nature) 16:21
- Clinical outcomes with Omicron (Nat Med) 23:02
- Low neutralizing antibodies induced by bivalent booster (NEJM) 30:38
- Antibody responses to bivalent booster (bioRxiV)
- Spike T cell responses not enhanced by bivalent booster (Sci Immunol)
- Pandemic end will not be televised (BMJ) 28:06
- Conflation of infection and disease (Twitter) 53:16
- Letters read on TWiV 952 1:09:24
- Timestamps by Jolene. Thanks!
Weekly Picks 1:30:22
Kathy – 10 moments for Jazz at Lincoln Center Orchestra Residency (Item 7) and Alan’s pick from TWiV 931 The Kissing Bug by Daisy Hernandez
Rich – Wilderness Safaris Photographic Competition 2022
Alan – Massachusetts Science Education Leadership Association, and the talk I gave to them last week
Vincent – Andrea Camillieri and his protagonist Inspector Montalbano
Listener Pick
Frank – Economics for the Future: Beyond the Superorganism
Debby – As routine vaccination rates fall, polio survivor hopes her story reverses urgent trend
Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
Please add a link for the Spike T shirts.
Here’s a link to the Vaccinated.us site in the meantime:
https://vaccinated.us/shop/
After the 14 minute mark as I listen Dr Scott goes on and on about no covid pneumonia. BS! Arn’t the stats hundreds of Covid fatalities per day? As I listen I hope you guys scure his butt.
What surprises me is that you didn’t ask Dr. Scott who should be the next NIAID Director. My candidate is another West Coast infectious diseases MD, Dr. Monica Gandhi. What do Daniel & Sara think?
I’d like to see MIT’s Michael B. Yaffe, who you’ve had on TWIV, made the next NIH Director.
In response to Justin’s letter, check out:
https://www.ecohealthalliance.org/career/internships
https://www.czbiohub.org/join/
https://www.criver.com/
Dr. Jake Scott’s perspective on Covid-19 was very informative and offered a differing take on the situation from Dr. Daniel Griffin. Both doctors have very good points to consider.
With regard to Dr. Scott’s endorsement of Bebtilovimab as a first-line treatment, my personal experience is that in September, when I was seeking out this drug for a patient there was one dose available in a multi-county region and the pharmacy informed me they could now bill Medicare and the patient for the medication at an expected cost of $4,000 without any assurance it would be paid for by Medicare or supplemental insurance.
This is in contrast to Paxlovid which does not have payment uncertainties yet. I fully understand that your podcast is science focused and not cost or economics focused, but the availability of the recommended drugs and its cost remain as major issues for the physicians and practitioners prescribing for Covid-19. Thanks.
Paul Blanchard, MD,
Petoskey, Michigan