TWiV 830: A culture of resistance

November 18, 2021

TWiV explains that a recent report suggesting that the SARS-CoV-2 spike protein inhibits V(D)J recombination in vitro would not impact immunity after infection or vaccination, and describes the isolation of remdesivir resistant mutants in cells in culture, and the emergence of amino acid changes in the spike protein identical to those in variants of concern, in the absence of immune selection.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 830 (77 MB .mp3, 128 min)
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Links for this episode

Weekly Picks 1:44:00

Kathy – When do we get back to normal? Maybe now.
RichThe Covid-19 Pandemic
AlanYaupon Brothers American tea
VincentCracking the genetic code (and Niremberg’s account)

Listener Picks

JustinPartisan vaccination
LisaThe Red Flag

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

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3 comments on “TWiV 830: A culture of resistance

  1. Did Alan mean Persian rather than Arabic? I’ve not been able to find the site he referred to about Covax 19. He says it is being distributed in Iran, so I would expect a web site to publish in Persian (aka Farsi)

  2. Steve Blake Nov 19, 2021

    The Coronavirus was fiddling while New York burned.