In COVID-19 clinical update #48, Daniel Griffin reviews effect of spike amino acid changes on neutralization with monoclonal antibodies, Sputnik V safety and efficacy results, increased reactogenicity after a single vaccine dose in seropositive individuals, single dose vaccination in seropositive health care workers, and results of three clinical trials on the use of anticoagulants.
Hosts: Daniel Griffin and Vincent Racaniello
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Links for this episode
- Resistance of variants to mAb neutralization (bioRxiv) 14:45
- Safety and efficacy of Sputnik V (Lancet) 19:00
- Increased vaccine reactogenicity in seropositives (medRxiv) 23:05
- Single dose vaccination in seropositive health care workers (medRxiv) 24:18
- Update on vaccine intervals (CDC) 25:48
- Single dose AZD1222 results (Lancet preprints) 34:02
- Three RCT on anticoagulants (NIH) 34:44
- Letters read on TWiV 716 44:48
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv
Thank you for TWIV!
I am a layperson and regular listener to TWIV and it has helped me get through this past year. Last year a colleague shared information on preparing one’s immune system to combat the virus from Eastern Virginia Medical School. Are you aware of these suggestions and is there any science to support them?
https://www.evms.edu/media/evms_public/departments/internal_medicine/Marik-Covid-Protocol-Summary.pdf
Regards,
Sheryl Bergen