Daniel Griffin provides a clinical report on COVID-19, then we discuss rapid deployment of SARS-CoV-2 testing by research laboratories in San Francisco, longitudinal observation of antibodies to SARS-CoV-2 in patients, and listener questions on vaccines, loss of smell, face masks, and more.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker
Guest: Daniel Griffin
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Download TWiV 677 (97 MB .mp3, 162 min)
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Links for this episode
- Daniel’s COVID-19 graph (Twitter) 2:07, 10:30
- Cornell U containment victory (Bloomberg) 5:51
- Regeneron mAb trial paused (WSJ) 59:55
- CLIAHUB (PLoS Path) 1:05:15
- Serum antibodies to SARS-CoV-2 over time (paper one, two, three) 1:17:45
- Letters read on TWiV 677 40:00, 1:54:35
- Timestamps by Jolene. Thanks!
Weekly Science Picks 2:25:45
Dickson – Comedy Wildlife Photography
Brianne – Ed Yong – Science reporting during a pandemic
Alan – Tree Story by Valerie Trouet
Rich – Vaccine Investigation and Online Information Network
Vincent – Wearing is Caring
Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
Great show guys.
Theres a typo in the COVID phases diagram: The time point in the diagram is T dvr but in the notes its Tvr. No biggie.
I think Dr. Griffin mentioned his graphic was going be accompanied by a publication. Is there a link to that somewhere? Maybe it’s not public yet.
Also, the story about the campers in South Dakota is tragic. Using HCQ/AZ as a standard of care, even in September, borders on malpractice. Are some doctors just not paying attention?? Ugh.
I’m sharing this graphic far and wide, especially to my friends who work in healthcare.
I have not found Daniel’s manuscript – when I do I’ll publicize.
I would listen, but only if Vincent & Co wears their masks during EVERY episode until the beloved vaccine arrives and then get a 100-fold dose of the vaccine from a double-blinded sample to prove it’s safety.
Just a note that Rich’s link above is messed up. Its probably http://www.violinet.org/
As an over 70yr old, following you for months, this news on developing therapeutics, antibodies etc has really given me hope. Thank you for all these brilliant updates. I have loved stretching my learning ( science graduate full 50 yrs ago! ) but remain intensely curious. Not all my friends share this love of science learning but this is one I,ll most certainly share. I just hope some of this travels across the Pond. It,s proving difficult to change direction over here!
Love the show, the main show and Dr. Griffen’s updates has really helped me and my colleagues keep up to date on the frontlines in the ED. Do you by any chance have the name of the Instagrammer or Twitterer who is posting summaries of the show? Would be great to have on weeks where I can’t listen.
Texas Ranks Highest In Total Number Of COVID-19 Cases In U.S.
(The nation’s second-most populous state surpassed California’s total as coronavirus cases continued to rise across the country.)
Ideology over reality?
One controversial debate on the horizon is whether Australia will let the Chinese students back in if they’ve had the Chinese vaccine. Our universities, and our economy as a whole, depend on the fees paid by international students. We’re also one of the only countries to have eliminated the virus.
Hi,
I would really like to get a copy of Daniel’s study on the benefits of using steroids + tozilizumab for early inflammatory phase patients like my uncle. I cannot find any references that look like the study he discusses at about minute 25. Searched medrxiv, google scholar, pubmed.
If you have it please forward the link.
Much appreciated.