TWiV reviews models for determining correlates of neutralizing antibody protection against COVID-19, and for identifying key vector and host species that drive transmission of zoonotic pathogens.
TWiV 791: A mad virologists’ T party
- August 8, 2021
- Tagged as: COVID-19, deer, mRNA vaccine, neutralizing antibody, pandemic, rhesus macaque, SARS-CoV-2, t cells, viral, virology, virus, viruses
TWiV reviews SARS-CoV-2 infection of wild white-tailed deer in the US, mRNA vaccine-mediated protection by spike-specific T cells before detection of neutralizing antibodies, and recovery from SARS-CoV-2 infection in T-cell depleted rhesus macaques.
The TWiVers analyze efficacy of the AstraZeneca/Oxford adenovirus vectored vaccine, SARS-CoV-2 did not infect miners who became ill 8 years ago after cleaning bat guano from a cave in Yunnan Province, and induction of antigen-specific germinal center responses and production of neutralizing antibody by SARS-CoV-2 mRNA vaccine but not purified protein.
TWiV 677: Does antibody really know what time it is?
- November 1, 2020
- Tagged as: coronavirus, COVID-19, face mask, neutralizing antibody, pandemic, SARS-CoV-2, Vaccine, viral, virology, virus, viruses
Daniel Griffin provides a clinical report on COVID-19, then we discuss rapid deployment of SARS-CoV-2 testing by research laboratories in San Francisco, longitudinal observation of antibodies to SARS-CoV-2 in patients, and listener questions on vaccines, loss of smell, face masks, and more.
TWiV 620: Antibodies and T cells in COVID-19 patients
- May 29, 2020
- Tagged as: antibody, B cell, CD4, CD8, COVID-19, neutralizing antibody, SARS-CoV-2, T cell, t cell epitope, viral, virology, virus, viruses
Jon Yewdell returns to explain studies on detection of antibodies and T cell epitopes in patients who have recovered from COVID-19.