Lisa joins TWiV to discuss her research on the pathogenesis of SARS-CoV, MERS-CoV, and SARS-CoV-2, including work on vaccines and an antiviral, then we review the SARS-CoV-2 spike protein as a potential analgesic, and listener questions.
Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler and Brianne Barker
Guest: Lisa Gralinski
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Download TWiV 674 (71 MB .mp3, 119 min)
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Links for this episode
- SARS-like bat CoV with potential for human emergence (Nat Med) 20:54
- SARS-CoV susceptibility loci in CC mice (PLoS Genetics) 30:05
- Combination attenuation for SARS-CoV vaccine (J Virol) 41:07
- Orally administered SARS-CoV-2 antiviral (Res Sq) 52:06
- Spike protein induces analgesia (Pain) 1:05:51
- Letters read on TWiV 674 1:21:20
- Timestamps by Jolene. Thanks!
Weekly Science Picks 1:48:53
Brianne – The Lonely Pipette Podcast: Mentoring with Harmit Malik
Kathy – Dr. Boyd the Chemist one and two GREAT short videos one and two, How to read an old school thermometer, New Marvel storyline, Wear a Mask parody of Be My Guest
Rich – Clear+Vivid with Alan Alda
Vincent – Immune 36: Aberrant immunity in COVID-19
Listener Pick
Ryan – Dr. Fauci on politicization of pandemic
Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
Regarding the discussion of the paper in “PAIN” (starting about minute 61): It is really refreshing or should I say interesting to see these serious scientists go through a paper outside of their areas of expertise. I good model of how to get a general idea of something without having to become expert. Also it is a good example of unexpected interaction of different not terribly closely related of different subjects. Thank you TWIV for delving into this.
Where do we find Timestamps by Jolene? I can’t find them on her Twitter. Would be awesome if they posted the Timestamps at the bottom of the episodes! Thanks
Doctor Vincent;
Still have that PDF converter if want it.
Where is this Odd Location app created by a listener at 1:30? My Google-fu is coming up with nothing. 🙁