The TWiVstars reveal the diversity of herpes simplex virus type 2 in a neonatal population, and parallel adaptation of rabbits in three countries to myxoma virus.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler
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Download TWiV 540 (66 MB .mp3, 109 min)
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Links for this episode
- Diversity of HSV2 in neonates (mSphere) 23:18
- Adaptation of rabbits to myxoma virus (Science) 49:16
- Principal component analysis (YouTube) 1:02:30
- Image credit
- Letters read on TWiV 540 3:05, 1:22:46
- Timestamps by Jolene. Thanks!
Weekly Science Picks 1:35:33
Alan – The Quarters
Rich – Brian May – New Horizons (Ultima Thule Mix) [Official Music Video]
Dickson – How rats became an inescapable part of city living
Kathy – Principal Component Analysis (short longer) and Educational Material about Influenza Viruses
Vincent – Why “chickenpox parties” are a terrible idea—in case it’s not obvious
Intro music is by Ronald Jenkees.
Send your virology questions and comments to firstname.lastname@example.org
Thanks for the great show!
Couldn’t stop laughing about your comments: It’s too GC rich!
The lab I worked in as a graduate student, We used to say this all the time when our PCRs of HSV-1 genes failed. Those failures helped me learn how to troubleshoot PCR reactions. At my current job, when I mention GC rich sequences in primers used for seuencing mitochondrial genome regions, people look at me like I’m crazy.
Hearing that comment brought back some great
PS I think the authors, when researching why the plaques were smaller forgot an area to look at: the packing of the viral genome into capsids. Perhaps capsids formation and/or packaging of the viral genome was not 100% efficient. Hence the smaller plaques.