Vincent, Dick, Alan, and Saul Silverstein revisit an ebolavirus needlestick accident, and discuss the role of TLR3 in formation of Negri bodies, a New England college closed by norovirus gastroenteritis, hand, foot, and mouth disease outbreak in China, and the exit of herpes simplex virus from latency by synthesis of VP16.
Vincent, Alan, and Rich Condit converse about induction of polyomavirus replication in multiple sclerosis patients treated with the MS drug Tysabri, the extent of human polyomavirus infection, selection of influenza vaccines for the 2009-10 season, cowpox virus transmission from animals to humans, vaccinia-like virus infecting humans and cattle in Brasil, and poxviruses.
Vincent, Alan, and Luis talk about rabies in Viet Nam and Angola, needle-stick infections with ebolavirus and West Nile virus, and viral evolution.
Vincent and Alan discuss cap-snatching by the hantavirus N protein and the influenza virus endonuclease, HIV-1 and Ebola virus antagonism of tetherin, and influenza pneumonia.
Vincent, Dick, and Alan discuss adenovirus type 36 and obesity, new influenza antiviral drugs, viral hemorrhagic septicemia virus of fish, and Ebola virus in pigs and pig farmers in the Phillipines.
Vincent, Dick, and Saul talk about discoveries in virology that have had a major impact on the field.
Vincent and Jeremy, in Saanen, Switzerland, review the 19th Challenge in Virology meeting, and implications of a new HIV-1 sequence from 1960 for the origin of AIDS.
Vincent, Dick, and Alan converse about hantavirus spread by large deer mice, why the 1918 influenza virus replicates in the lower respiratory tract, measles in Europe, and the growing resistance of influenza virus to antivirals.
Vincent and Alan discuss a viral upper respiratory tract infection, transmission of H5N1 influenza virus, death of an HIV denialist, and the Ebola outbreak in the Democratic Republic of the Congo.
Vincent and Alan talk about President-elect Obama’s choices for his science advisors, SARS sensationalism, a new enteric picornavirus, and the top 10 virology stories of 2008.