Nels joins TWiV to reveal the discovery of a picornavirus of zebrafish by measuring immune responses in the host, genome sequence analysis of the White House COVID-19 outbreak, and a six-fold higher SARS-CoV-2 exposure rate than reported cases in German children.
The TWiVsters review isolation of a naturally occurring DNA virus from fruit flies, and the cell-type specific function of a small transmembrane protein encoded in an open reading frame upstream of the enterovirus polyprotein.
The TWiVaniellos discuss a thermostable poliovirus empty capsid vaccine, and two cell genes that act as a switch between entry and clearance of picornavirus infection.
The TWiVniks consider the role of a cell enzyme in removing a protein linked to the 5′-end of the picornavirus genome, and the connection between malaria, Epstein-Barr virus, and endemic Burkitt’s lymphoma.
For a TWiV Thanksgiving, Vincent, Alan, and Kathy trace the feud over genome editing, a new virus discovered in human blood, and the origins of hepatitis A virus.
The TWiV team discusses the possible association of the respiratory pathogen enterovirus D68 with neurological disease.
The TWiVocateurs discuss how the RNA polymerase of enteroviruses binds a component of the splicing machinery and inhibits mRNA processing.
The TWiVers discuss the growing Ebola virus outbreak in West Africa, and an epidemic of respiratory disease in the US caused by enterovirus D68.
Vincent meets up with Janet Butel and Rick Lloyd at Baylor College of Medicine to talk about their work on polyomaviruses and virus induced stress.
Vincent, Alan, Rich and Kathy review a protease essential for influenza pathogenesis in mice, and directionality of rhinovirus RNA exit from the capsid.
The Hosts of TWiV
Vincent Racaniello, Ph.D.
Brianne Barker, Ph.D.
Rich Condit, Ph.D.
Dickson D.
Despommier, Ph.D.
Alan Dove, Ph.D.
Daniel Griffin, M.D.,
Ph.D., CTropMed CTH
Angela Mingarelli, DVM
Jolene Ramsey, Ph.D.
Kathy Spindler, Ph.D.