TWiV reviews the difficulties in predicting species susceptibility to SARS-CoV-2 infection by only examining the ACE2 protein, and the olfactory mucosa as a portal of entry into the central nervous system in COVID-19 patients.
TWiV 572: Your EV-D68th nervous breakdown
- November 3, 2019
- Tagged as: acute flaccid myelitis, AFM, astrocytes, cerebrospinal fluid, CSF, enterovirus D68, neurons, neurotropic, poliovirus, serology, viral, virology, virus, viruses
Amy joins the TWiV team to review evidence that enterovirus D68 is an etiologic agent of childhood paralysis, and her finding that the ability of the virus to infect cells of the nervous system is not a recently acquired property.
TWiV 527: City mouse, country mouse
- December 30, 2018
- Tagged as: deer mouse, enteric nervous system, flavivirus, hantavirus, hantavirus pulmonary syndrome, IBS, inflammatory bowel syndrome, intestinal dysmotility syndrome, neurotropic, outbreak, Peromyscus maniculatus, sin nombre virus, viral, virology, virus, viruses, west nile virus, zoonosis
The TWiV team summarizes the discovery of Sin Nombre virus, and presents evidence that neurotropic flaviviruses can cause intestinal dysmotility syndromes after systemic infection of mice.
From the Vector-Borne Viruses Symposium in Hamilton, Montana, Dickson and Vincent speak with Diane Griffin about her career and her work on understanding viral infections of the central nervous system.