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innate immunity

TWiV 224: A wide receiver and a natural defense

  • March 17, 2013

Vincent, Alan, Kathy, and Dickson discuss identification of a cell receptor for the coronavirus-EMC, and the role of interferon-epsilon in protecting the female reproductive tract.

TWiV 214: This is your brain on polyomavirus

  • January 6, 2013

Vincent, Alan, and Kathy discuss how coagulation factor X binding to adenovirus activates the innate immune system, and a novel polyomavirus associated with brain tumors in raccoons.

TWiV 206: Viral turducken

  • November 11, 2012

Vincent, Alan, Dickson, and Kathy discuss how the innate immune response to viral infection influences the production of pluripotent stem cells, and the diverse mobilome of giant viruses.

TWiV 198: Pox has got a squeeze-box, seals are gonna sneeze all night

  • September 2, 2012

Vincent, Alan, Rich, and Kathy review fatal avian influenza virus in harbor seals, and poxvirus deployment of genomic accordions to counter antiviral defenses.

TWiV 181: ORFan poxviruses and nIRFing prions

  • April 29, 2012

Vincent, Rich, and Kathy discuss Cotia virus, a new poxvirus, Orf virus infections associated with handling goats and lamb, and the innate immune response to prions.

TWiV 175: More than one way to skin a virus

  • March 18, 2012

Vincent, Alan, and Matt discuss herpes simplex encephalitis in children with innate immune deficiency, and the local response to microneedle-based influenza skin immunization.

TWiV 157: Better innate than never

  • November 13, 2011

A large TWiV panel remembers Ralph Steinman, and considers a new innate sensor of retroviral capsids.

TWiV 153: Rabid reindeer and protective prions

  • October 16, 2011

Vincent, Alan, and Rich review an outbreak of rabies in arctic foxes and reindeer in Norway, and a prion that makes you go antiviral.

TWiV 138: RISCy business with Raul Andino

  • June 19, 2011

Vincent meets up with Raul Andino in San Francisco to discuss the RNAi-based antiviral defense system of Drosophila, the fruit fly, and how it is antagonized by viruses.

TWiV 121: Huskies go viral

  • February 20, 2011

A conversation about careers in virology, systems biology, innate immunity, and antiviral research recorded at the University of Washington in Seattle.

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The Hosts of TWiV

Vincent Racaniello, Ph.D.


Brianne Barker, Ph.D.


Rich Condit, Ph.D.


Alan Dove, Ph.D.


Daniel Griffin, M.D.,
Ph.D., CTropMed CTH


Angela Mingarelli, DVM


Jolene Ramsey, Ph.D.


Kathy Spindler, Ph.D.


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