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Tag: genome

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TWiV 474: Call me fish meal

  • December 31, 2017
  • Tagged as: Bodo saltans virus, concatenated DNA, evolution, genome, giant virus, kinetoplastic, microzooplankton, mimivirus, tRNA, viral, virology, virus, viruses

The TWiVanguardians take on Bodo saltans virus, a leviathan which infects an abundant flagellated eukaryote in Earth’s waters.

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  • Episodes
  • Netcast

TWiV 398: Permission to be intuitive

  • July 17, 2016
  • Tagged as: cleavage, DNA damage response, dna replication, genome, herpes simplex virus, herpesvirus, packaging, recombination, Sandra Weller, viral, virology, virus, viruses
TWiV

Vincent speaks with Sandy Weller about her career and her work on the mechanisms of synthesis, maturation, cleavage and packaging of viral DNA genomes.

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  • Episodes
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TWiV 376: The flavi of the month is Zika

  • February 14, 2016
  • Tagged as: Aedes, brain, congenital rubella syndrome, dengue, genome, guillain-barré, microcephaly, mosquito, ocular defects, TORCH, viral, virology, virus, viruses, west nile virus, Zika, Zika virus
TWiV

The TWiV team discuss the latest data on Zika virus, including ocular defects in infants with microcephaly, and isolation of the entire viral genome from fetal brain tissue.

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  • Netcast

TWiV 268: Transmission is inevitable

  • January 19, 2014
  • Tagged as: aphid, bat, cauliflower mosaic virus, caulimovirus, Coursera, cytoskeleton, flight, fomite, genome, immunity, pararetrovirus, physician office, transmission, vector, viral, virology, virus

Vincent, Alan, Kathy, and Ashlee discuss fomites in physicians offices, plant virus factories involved in aphid transmission, and clues from the bat genome about flight and immunity.

3 Replies
  • Netcast

TWiV 267: Snow in the headlights

  • January 12, 2014
  • Tagged as: capillary electrophoresis, fluorescence correlation microscopy, genome, HA cleavage, influenza, pathogenesis, picornavirus, protease, rhinovirus, Tmprss2, uncoating, viral, virology, virus

Vincent, Alan, Rich and Kathy review a protease essential for influenza pathogenesis in mice, and directionality of rhinovirus RNA exit from the capsid.

1 Reply
  • Netcast

TWiV 246: Pandora, pandemics, and privacy

  • August 18, 2013
  • Tagged as: avian influenza H7N9, fouchier, gain of function, genome, hela, Henrietta Lacks, kawaoka, mimivirus, Pandoravirus, sequence, viral, virology, virus

Vincent, Alan, Rich, and Kathy discuss the huge Pandoravirus, virologists planning H7N9 gain of function experiments, and limited access to the HeLa cell genome sequence.

2 Replies
  • Netcast

TWiV 215: Illuminating rabies and unwrapping a SARI

  • January 13, 2013
  • Tagged as: coronavirus, EMC, genome, Middle East, neuron, rabid, rabies, receptor, SARI, SARS, tropism, viral, virology, virus

Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Vincent, Alan, and Kathy review the finding that rabies virus infection alters but does not kill neurons, and provide an update on the novel coronavirus in the Middle…

1 Reply
  • Netcast

TWiV 187: The mummy

  • June 10, 2012
  • Tagged as: ancient dna, autoantibody, genome, HBV, hepatitis b virus, ipop, Korea, metabolome, mike snyder, mummy, personal omics profiling, proteome, respiratory syncytial virus, rhinovirus, transcriptome, viral, virology, virus

Vincent and Rich discuss recovery of a hepatitis B viral genome from a 16th century Korean mummy, and personal omics profiling of an individual over a 14 month period.

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  • Netcast

TWiV 139: Honey, I shrunk the virus

  • June 26, 2011
  • Tagged as: allopatric, amoeba, colony collapse disorder, gene deletion, genome, honey bee, microbiome, mimivirus, sympatric, viral, virology, virus

Vincent, Alan, and Dickson discuss the reduction in genome size of Mimivirus upon passage in amoeba, and analysis of the microbiome of honeybees.

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  • Netcast

TWiV 106: Making viral DNA II

  • November 6, 2010
  • Tagged as: adenovirus, DNA, dna synthesis, double helix, genome, herpesvirus, parvovirus, polymerase, poxvirus, replication, viral, virology, virus

Vincent, Dickson, and Rich continue Virology 101 with a second installment of their discussion of how viruses with DNA genomes replicate their genetic information.

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