Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler
Vincent, Alan, Rich, and Kathy discuss the huge Pandoravirus, virologists planning H7N9 gain of function experiments, and limited access to the HeLa cell genome sequence.
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Download TWiV 246 (62 MB .mp3, 86 min)
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Links for this episode:
- Pandoraviruses (Science)
- Unlike anything seen before (virology blog)
- H7N9 gain of function experiments planned (Nature, Science)
- Virologists plan H7N9 gain of function experiments (virology blog)
- Creating a deadly virus? Not!! (USA Today)
- HeLa cell genome sequence (Nature)
- NIH Director explains HeLa agreement (Nature)
- HeLa deal (Nature)
- Biospecimen policy (Nature)
- Sequencing HeLa the right way (turbidplaque)
- Skloot on HeLa deal (The Scientist)
- HeLa deal (NY Times, USA Today)
- Picture on Condit’s wall (EID)
- Letters read on TWiV 246
- Video of this episode – view below or at YouTube
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Rich – 1981 primitive internet report (YouTube)
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Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv
In week 2 of the Coursera class I’m currently taking, we learned that a cell is either Susceptible, Permissive or both. We learned that a susceptible cell is a cell that has a receptor for a virus while a permissive cell has the components to support viral replication.
…Enter this plant virus you speak about in this episode which doesn’t require a surface receptor. Does this now mean that all plant cells are susceptible? Are there any examples of human/animal viruses which don’t require a surface receptor?
To me, this seems like a fundamental distinction…a “principal” of virology 🙂
In week 2 of the Coursera class I’m currently taking, we learned that a cell is either Susceptible, Permissive or both. We learned that a susceptible cell is a cell that has a receptor for a virus while a permissive cell has the components to support viral replication.
…Enter this plant virus you speak about in this episode which doesn’t require a surface receptor. Does this now mean that all plant cells are susceptible? Are there any examples of human/animal viruses which don’t require a surface receptor?
To me, this seems like a fundamental distinction…a “principal” of virology 🙂