TWiV reveals a prediction of the expected endemic seasonality of COVID-19, based on circulation of human coronaviruses, and ecological clearance of vaccine-targeted human papillomaviruses and an increase in circulation of non-targeted virus types.
TWiV notes the passing of Harald zur Hausen, dengue breaking records in the Americas, inhibition of SARS-CoV-2 infection and inflammation by modulation of type I IFN, and an armed nanobody that protects mice against influenza A and B disease.
Patrick Moore returns to TWiV to discuss the discovery from the Chang-Moore laboratory of circular RNAs in cells infected with herpesviruses.
The TWiV team is together in New York City for a conversation with Nobel Laureate Harold Varmus about his remarkable career in science.
From ASV 2016 at Virginia Tech, Vincent, Rich and Kathy speak with Stephen Russell about his career and his work on oncolytic virotherapy – using viruses to treat cancers.
The TWiVniks consider the role of a cell enzyme in removing a protein linked to the 5′-end of the picornavirus genome, and the connection between malaria, Epstein-Barr virus, and endemic Burkitt’s lymphoma.
Vincent speaks with Blossom about her laboratory’s research on Kaposi’s sarcoma-associated herpesvirus, including how it transforms cells, the switch between lytic and latent replication, and its interaction with the innate immune system of the host.
Tre TWiV amici present three snippets and a side of sashimi: how herpesvirus inhibits host cell gene expression by disrupting transcription termination.
Vincent speaks with John Coffin about his career studying retroviruses, including working with Howard Temin, endogenous retroviruses, XMRV, chronic fatigue syndrome and prostate cancer, HIV/AIDS, and his interest in growing cranberries.
Vincent meets up with Janet Butel and Rick Lloyd at Baylor College of Medicine to talk about their work on polyomaviruses and virus induced stress.