At Aarhus University in Denmark, Vincent speaks with Trine Mogensen, Søren Paludan, Ole Søgaard, and Madalina Carter-Timofte about their careers and their work on sensing herpesviral DNA, immunodeficiencies that predispose to severe viral infections, and the path to a cure for HIV/AIDS.
TWiV 551: Golden hands
- June 9, 2019
- Tagged as: AIDS, Cold Spring Harbor Laboratory, hiv-1, retrovirus, viral, virology, virus, viruses
At Retroviruses 2019 in Cold Spring Harbor, Vincent speaks with virologist Bryan Cullen about his work and his career, together with former associates Ann Skalka, Paul Bieniasz, and Michael Malim.
Ned Landau joins the TWiV team to discuss restriction of HIV replication by SAMHD1, and a viral antagonist that can be used to produce a dendritic cell vaccine.
Vincent and Dickson travel to the 44th Retrovirus meeting at Cold Spring Harbor Laboratories, where they speak with John Coffin, Stephen Hughes, Ya-Chi Ho, and Matt Takata about the meeting and their work on HIV-1.
Vincent and the Virals review undermining of antiviral effectiveness by genital inflammation, and heterogeneity of influenza virus infection in single cells.
Theodora Hatziioannou joins the TWiV team to discuss a macaque model for AIDS, and how a cell protein that blocks HIV-1 infection interacts with double-stranded RNA.
Vincent speaks with Gary Nabel, Chief Scientific Officer at Sanofi and former Director of the Vaccine Research Institute of NIAID, on his career and his work on HIV vaccines.
The Fellowship of the Virus trace the early history of HIV in North America, based on genome sequences obtained from archival sera from the late 1970s, which also reveal that Gaetan Dugas was not Patient Zero.
TWiV 409: A Nef is enough
- October 2, 2016
- Tagged as: AIDS, endocytosis, hiv, Nef, restriction factor, SERINC, siv, viral, virion, virology, virus, viruses
Jeremy joins the TWiVeroids to tell the amazing story of how the function of the HIV-1 protein called Nef was discovered and found to promote infection by excluding the host protein SERINC from virus particles.
TWiV 408: Boston Quammens
- September 25, 2016
- Tagged as: AIDS, chimp, David Quammens, ebola virus, hiv, science writing, siv, spillover, viral, virology, virus, viruses, Zika virus, zoonosis
Four years after filming ‘Threading the NEIDL’, Vincent and Alan return to the National Emerging Infectious Diseases Laboratory BSL4 facility at Boston University where they speak with science writer David Quammen.