Paul Offit returns to TWiV to discuss new CDC guidance on J&J vaccine, why children should be immunized against COVID-19, and whether or not booster doses are scientifically justified.
TWiV reviews the vials labeled smallpox that were not, re-emergence of enterovirus D68 in Europe, efficacy of inactivated SARS-CoV-2 vaccine, and cellular correlates of protection for an oral influenza virus vaccine.
TWiV 827: A shot to save the world with Greg Zuckerman
- November 7, 2021
- Tagged as: adenovirus vector, BioNTech, coronavirus, COVID-19, Moderna, mRNA vaccine, Novavax, pandemic, Pfizer, SARS-CoV-2, Vaccine, viral, virology, virus, viruses
Greg Zuckerman joins TWiV to discuss his book that explores the race to produce COVID-19 vaccines, with insights into the companies, scientists, and executives involved and the rivalries, ambitions, ego, and a desire to save the world.
TWiV examines the claim by Brazil’s ANVISA that the Sputnik vaccine contains replication-competent adenovirus, and a role for the furin cleavage site in SARS-CoV-2 spike for efficient reproduction in the respiratory tract, evasion of antiviral IFITM proteins, and transmission in ferrets.
TWiV 726: Molecular animator Janet Iwasa
- March 4, 2021
- Tagged as: adenovirus vector, COVID-19, J&J vaccine, Maya, molecular animation, pandemic, SARS-CoV-2, viral, virology, viruses
Janet Iwasa joins TWiV to recount how she became a molecular animator, including a pivot during her Ph.D. thesis research, the value of animations in science, and their latest animation of SARS-CoV-2 entry into cells.
Daniel Griffin provides a clinical report on COVID-19, review of the phase I and II trials of the Russian prime-boost vaccine, a mouse model that recapitulates age-dependent severe disease, and listener questions.