BARDA_LOGOHosts: Vincent RacanielloRich Condit, and Ed Niles

Vincent, Rich, and Ed discuss the transition from academic scientist to government work, the general program of drug and vaccine development in the biodefense world and at BARDA, and career opportunities for scientists in government.

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Rich – Dark Sun: The Making of the Hydrogen Bomb by Richard Rhodes
Ed – Tenth anniversary of the human genome at Science Magazine
Vincent – Poliovirus fights back

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science journalismHosts: Vincent Racaniello and David Tuller

Vincent and journalist David Tuller converse about the state of science reporting by the press.

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Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich answer listener questions about vaccinia virus, fungal viruses, synthetic viruses, influenza vaccine, HeLa cells, multiplicity of infection, and much more.

Click the arrow above to play, or right click to download TWiV #118 (68 MB .mp3, 94  minutes).

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Alan – What you need to know about infectious disease
Rich – Bad Project (YouTube)
Vincent – Federal research center will help develop medicines

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panic virusHosts: Vincent RacanielloRich Condit, and Seth Mnookin

Vincent and Rich converse with Seth Mnookin, author of The Panic Virus, about vaccines, autism, thimerosal, and a contagion of human unreason run wild.

Click the arrow above to play, or right click to download TWiV #117 (69 MB .mp3, 96  minutes).

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Rich and Vincent – The Panic Virus by Seth Mnookin

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<p”>hive and feeding bottlesHosts: Vincent RacanielloAlan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich review an adenovirus-based vaccine strategy against drug addiction, a field trial of RNAi to prevent Israeli acute paralysis virus infection in honeybees, and suppression of avian influenza transmission in transgenic chickens.

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Dickson – Brian Deer’s investigation of Andrew Wakefield
Rich –
Photographic periodic table of the elements
Alan – Year of the bat (site one and site two)
Vincent – EteRNA (NY Times article)

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brainbow pseudorabies virusHosts: Vincent RacanielloAlan DoveRich Condit, and Marc Pelletier

Vincent, Alan, Rich and Marc discuss the finding that a limited number of incoming herpesviral genomes can replicate and express in a cell, and controlling viral replication in Aedes aegypti with a Wolbachia symbiont.

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Marc – Homebrew bioreactor (photo, movie) – culture bottle and drive, oil-free vacuum pumps
Rich –
Logitech Harmony Universal Remote
Alan – H.M.S. Challenger Reports
Vincent – Sequence of the strawberry genome and blog post by lead author

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vaccinia plaqueHosts: Vincent RacanielloAlan Dove, and Rich Condit

Vincent, Alan, and Rich revisit ten compelling virology stories of 2010.

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Ten virology stories of 2010:

  1. XMRV, CFS, and prostate cancer (TWiV 113, 99, 98, 94, 89, 76, 70, 65)
  2. The ongoing saga of polio eradication (TWiV 110, 79)
  3. Viruses interact with the miRNA/siRNA system (TWiV 108, 72)
  4. Endogenous viruses – retro and beyond (TWiV 105, 91, 88, 65)
  5. Dengue virus progress and new outbreak (TWiV 111, 95, 82)
  6. Colony collapse disorder (TWiV 104)
  7. David Baltimore (TWiV 100)
  8. Ode to a plaque (TWiV 68)
  9. Vaccine contamination with circovirus (TWiV 86, 77, 75)
  10. Universal influenza vaccines (TWiV 107)

Weekly Science Picks

Rich – Elementary schoolchildren publish a science paper (original article and editorial with video) – thanks Kathy!
Alan – White-nose syndrome blog
Vincent – Headway, headlines and healthy skepticism

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rich conditHosts: Vincent RacanielloAlan DoveRich Condit, and Alan Rein

Vincent, Alan, and Rich discuss the retrovirus XMRV with retrovirologist Alan Rein of the National Cancer Institute.

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Rich – Word Lens
Alan – Tetenal Press Kit
Vincent – In the pipeline and Things I won’t work with by Derek Lowe

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dickson despommierHosts: Vincent RacanielloAlan Dove, and Rich Condit

Vincent, Alan, and Rich review the making of a virulent poxvirus by insertion of the gene encoding IL-4, and severe 2009 H1N1 influenza due to pathogenic immune complexes.

Click the arrow above to play, or right-click to download TWiV #112 (71 MB .mp3, 98 minutes). To download, right-click or control-click on the link, then select save as.

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Rich – The Scientist’s Top 10 Innovations 2010
Alan – Avian Vocalizations Center
Vincent – Microbial soap from Cleaner Science (thanks, Nadia!)

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Hosts: Vincent RacanielloAlan DoveRich Condit, Ed Fussell, Andrea Leal, and Amy Sargent

The TWiV crew meets with members of the Florida Keys Mosquito Control District at Florida Gulf Coast University to discuss dengue in Florida and how to control it.



Click the arrow to play, or right-click to download TWiV #111 (76 MB .mp3, 105 minutes).

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Weekly Science Picks

Rich – At the Bench, A Laboratory Navigator by Kathy Barker
Alan – DEEP Indonesia Underwater Photo Contest 2010 Winners
Vincent –
HHMI resources for early-career scientists

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TWiV at FGCU