TetraselmisFrom the TWiV team, human cowpox infection possibly acquired from a pet cat, and a new giant mimivirus of green algae with genes encoding enzymes of fermentation.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler

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KathyLandscapes that look like another world (but they are from Spain)
RichBrighton Collaboration; Viral Vector Vaccines Safety Working Group (V3SWG) (Chen & DeStefano: Vaccine adverse events: causal or coincidental?)
DicksonClouds of Jupiter and EBNA2 and autoimmunity
Vincent – More than one-third of graduate students report being depressed (original article)

Intro music is by Ronald Jenkees.

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Vincent visits Sandra Urdaneta-Hartmann at Drexel University College of Medicine in Philadelphia to talk about the development of the mobile video game ‘CD4 Hunter’.

Host: Vincent Racaniello

Guest: Sandra Urdaneta-Hartmann

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Download TWiV 489 (40 MB .mp3, 66 min)
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Intro music is by Ronald Jenkees.

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Olfactory virus spreadThe TWiV team reveals that recent mumps virus outbreaks in the US are due to waning vaccine efficacy, and an intranasally delivered small interfering RNA that controls West Nile infection in the brain.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, and Kathy Spindler

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KathyPeak bloom and photographing cherry blossoms
DicksonOrigins of vertebrate RNA viruses
AlanRare footage of anglerfish in the deep ocean
Vincent – NIH must reduce disparities in funding

Listener Picks

Mariann – Eden Project and Bellyvision Apparatus and the Like
AmirWinners of ICR Science Photography and Photography Contest

Intro music is by Ronald Jenkees.

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Vera TarakanovaAt the Medical College of Wisconsin, Vincent talks with current and former members of the Department of Microbiology and Immunology about their work and their careers.

Host: Vincent Racaniello

Guests: Dominique Carter, Sid Grossberg, John Kirby, Scott Terhune, and Vera Tarakanova

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Download TWiV 487 (38 MB .mp3, 63 min)
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Intro music by Ronald Jenkees

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Hap-1 cell karyotypeSean Whelan returns to TWiV to speak with Vincent about using haploid cell lines to identify genes encoding cell receptors for viruses, including Ebolavirus, Lassa virus, and more.

Host: Vincent Racaniello

Guest: Sean Whelan

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Intro music by Ronald Jenkees

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winefrontThe TWiV posse considers viral insulin-like peptides encoded in fish genomes, and insect antiviral immunity by production of viral DNA from defective genomes of RNA viruses.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Kathy Spindler, and Brianne Barker

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KathyVegas casinos lost money on physicists
BrianneAstronaut twin’s DNA is not 7% different!
DicksonParasitic Diseases lecture videos
AlanIn Season blog by Donna Long
Vincent – Buckyball viruses

Listener Picks

Paul – Wine labels (front, back)

Intro music is by Ronald Jenkees.

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tupanvirusThe TWiVumvirate discuss the giant Tupanvirus, with the longest tail in the known virosphere, and dampened STING dependent interferon activation in bats.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Kathy Spindler, and Brianne Barker

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Download TWiV 484 (53 MB .mp3, 87 min)
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KathyHow to read a phylogenetic tree
BrianneNo immune overload for vaccines
DicksonFlowchart of viral families
AlanLetters to a Pre-Scientist
Vincent – True believers, entrepreneurs, and scammers in alternative medicine and Simply Put: Vaccines Save Lives

Listener Picks

Vinayaka – Code of Ethics for Young Scientists
MattTWiV 443

Intro music is by Ronald Jenkees.

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deFonbrune chamberVincent and the Virals review undermining of antiviral effectiveness by genital inflammation, and heterogeneity of influenza virus infection in single cells.

Hosts: Vincent RacanielloAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 483 (61 MB .mp3, 101 min)
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KathyDance Dance
Rich – Snopes
AlanNext Generation Science Standards
Vincent – TWiEVO 28: Genetics of skin pigmentation in Africa

Intro music is by Ronald Jenkees.

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Aedes aegyptiThe TWiV Masters discuss serologic evidence of Ebolavirus infection in a population with no outbreaks, and the set of endogenous viral elements in the mosquito genome.

Hosts: Vincent Racaniello, Dickson DespommierAlan DoveKathy Spindler, and Brianne Barker

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Download TWiV 482 (59 MB .mp3, 98 min)
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KathyOrigami sound barrier
BrianneiBiology
DicksonSwitched-on bats
AlanHawaii’s communication breakdown
Vincent – Inside the Federal Bureau of way too many guns and What I Saw Treating Parkland Victims

Listener Pick

JohnyeDebunking Anti-Vaxxers

Intro music is by Ronald Jenkees.

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CoronavirusThe TWiVodrome considers the intestinal tract as an alternative infection route for MERS coronavirus, and how reduced accumulation of defective viral RNAs might lead to severe influenza.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 481 (62 MB .mp3, 102 min)
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Weekly Science Picks

KathyCD45.1 and CD45.2 mice may not be functionally equivalent
RichRelative humidity versus dewpoint (video)
DicksonUnderwater photography winners
AlanPhoto of a single atom
Vincent – Proposed Federal science budget cuts and The Blog is Dead

Listener Pick

JessLouis Tompkins Wright

Intro music is by Ronald Jenkees.

Send your virology questions and comments to [email protected]